| Literature DB >> 19174775 |
Saskia N de Wildt1, Nobuko Taguchi, Gideon Koren.
Abstract
BACKGROUND: A 27-year-old woman with upper mediastinum stage IIA Hodgkin lymphoma was treated with six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Two months later she received a total of 4,250 cGy to the upper mediastinum and left clavicular region over a 1-month period. One week after completion of radiotherapy she was found to be 13-weeks pregnant. Her physician advised her to terminate pregnancy. She contacted a teratology information service for further information regarding the risks of radiation exposure for her fetus. INVESTIGATIONS: Estimation of fetal radiation exposure, literature review and synthesis of published cases and effects of fetal radiation exposure. DIAGNOSIS: Estimated fetal radiation dose between 5 and 18 cGy. MANAGEMENT: Counseling on the possible risks to the fetus as a result of radiation exposure.Entities:
Mesh：
Year: 2009 PMID： 19174775 DOI： 10.1038/ncponc1320
Source DB: PubMed Journal: Nat Clin Pract Oncol ISSN： 1743-4254