| Literature DB >> 19174236 |
Liying Wang1, Ying Sun, Jian Wang, Xiaonan Zhu, Fei Jia, Yanbo Cao, Xinghua Wang, Hanqi Zhang, Daqian Song.
Abstract
Based on well-known silver mirror reaction the Ag film was formed on Au film modified by self-assembled monolayer (SAM) of 1,6-hexanedithiol (HDT). The sensitivity of the biosensor based on this Ag/Au film is enhanced compared to that based on Au film. When the surface plasmon resonance (SPR) biosensor based on this Ag/Au film was used to determine human IgG, the range of concentrations of human IgG that could be determined is 0.30-40.00 microg mL(-1). The lowest concentration (0.30 microg mL(-1)) that could be detected was about 8 times lower than that obtained by the biosensor without modification by Ag film (2.50 microg mL(-1)), which demonstrated that the biosensor based on Ag/Au film could make the resonant wavelength move to longer wavelength following with the sensitivity enhancement of the SPR biosensor.Entities:
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Year: 2008 PMID： 19174236 DOI： 10.1016/j.talanta.2008.11.019
Source DB: PubMed Journal: Talanta ISSN： 0039-9140 Impact factor: 6.057