Literature DB >> 19172699

Haemoglobin, C-reactive protein and androgen levels in uncomplicated and complicated pregnancies of women with polycystic ovary syndrome.

Eszter Vanky1, Kjell A Salvesen, Arne Asberg, Sven M Carlsen.   

Abstract

OBJECTIVE: We studied a possible association between pregnancy complications and blood/serum levels of haemoglobin, C-reactive protein, sex hormones and lipids in women with polycystic ovary syndrome.
MATERIAL AND METHODS: Twenty-one women with polycystic ovary syndrome were followed prospectively from the first trimester to delivery. Women with pregnancy complications (n=10) were compared to women without complications (n=11). Outcome measures were blood/serum levels of haemoglobin, C-reactive protein, dehydroepiandrosterone sulphate, androstenedione, testosterone, sex hormone binding globulin, free testosterone index, oestrogens and lipids.
RESULTS: Haemoglobin levels were higher in complicated pregnancies compared to uncomplicated pregnancies throughout the complete pregnancy, while C-reactive protein levels were higher for complicated pregnancies at gestational weeks 19 and 32. Serum levels of lipids, androgens and oestrogens did not differ throughout pregnancy.
CONCLUSION: In women suffering from polycystic ovary syndrome, pregnancy complications were associated with elevated blood/serum levels of haemoglobin and C-reactive protein. Androgen, oestrogen and lipid levels did not differ between groups.

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Year:  2008        PMID: 19172699     DOI: 10.1080/00365510701810613

Source DB:  PubMed          Journal:  Scand J Clin Lab Invest        ISSN: 0036-5513            Impact factor:   1.713


  2 in total

Review 1.  Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis.

Authors:  Héctor F Escobar-Morreale; Manuel Luque-Ramírez; Frank González
Journal:  Fertil Steril       Date:  2010-12-17       Impact factor: 7.329

2.  Changes in androgens and insulin sensitivity indexes throughout pregnancy in women with polycystic ovary syndrome (PCOS): relationships with adverse outcomes.

Authors:  Angela Falbo; Morena Rocca; Tiziana Russo; Antonietta D'Ettore; Achille Tolino; Fulvio Zullo; Francesco Orio; Stefano Palomba
Journal:  J Ovarian Res       Date:  2010-10-13       Impact factor: 4.234

  2 in total

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