Literature DB >> 19172403

Current techniques for the study of troponin I phosphorylation in human heart.

Clare E Gallon1.   

Abstract

Cardiac troponin I phosphorylation has been shown to be reduced in human heart failure and hypertrophic cardiomyopathy using the increasingly popular Pro-Q Diamond phosphoprotein gel stain. In this brief report I discuss the use of Western immunoblotting, non-equilibrium isoelectric focussing and Pro-Q Diamond and introduce phosphate affinity SDS-PAGE using Phos-tag-acrylamide for the investigation of troponin I phosphorylation.

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Year:  2009        PMID： 19172403     DOI： 10.1007/s10974-009-9170-4

Source DB:  PubMed          Journal:  J Muscle Res Cell Motil        ISSN： 0142-4319            Impact factor:   2.698


  19 in total

1.  Label-free kinase profiling using phosphate affinity polyacrylamide gel electrophoresis.

Authors:  Emiko Kinoshita-Kikuta; Yuri Aoki; Eiji Kinoshita; Tohru Koike
Journal:  Mol Cell Proteomics       Date:  2006-11-05       Impact factor: 5.911

2.  Microanalysis and distribution of cardiac troponin I phospho species in heart areas.

Authors:  P Ardelt; P Dorka; K Jaquet; L M Heilmeyer; H Körtke; R Körfer; G Notohamiprodjo
Journal:  Biol Chem       Date:  1998-03       Impact factor: 3.915

3.  Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

Authors:  M R Bristow; R Ginsburg; V Umans; M Fowler; W Minobe; R Rasmussen; P Zera; R Menlove; P Shah; S Jamieson
Journal:  Circ Res       Date:  1986-09       Impact factor: 17.367

4.  Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure.

Authors:  Andrew E Messer; Adam M Jacques; Steven B Marston
Journal:  J Mol Cell Cardiol       Date:  2006-11-01       Impact factor: 5.000

5.  Reduced contractile responses to forskolin and a cyclic AMP analogue in myocytes from failing human ventricle.

Authors:  S E Harding; S M Jones; G Vescovo; F Del Monte; P A Poole-Wilson
Journal:  Eur J Pharmacol       Date:  1992-11-13       Impact factor: 4.432

6.  Troponin phosphorylation and myofilament Ca2+-sensitivity in heart failure: increased or decreased?

Authors:  Steven B Marston; Pieter P de Tombe
Journal:  J Mol Cell Cardiol       Date:  2008-07-19       Impact factor: 5.000

7.  Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle.

Authors:  Adam M Jacques; O'Neal Copeland; Andrew E Messer; Clare E Gallon; Katie King; William J McKenna; Victor T Tsang; Steven B Marston
Journal:  J Mol Cell Cardiol       Date:  2008-06-04       Impact factor: 5.000

8.  Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes.

Authors:  So-ichiro Yasuda; Pierre Coutu; Sakthivel Sadayappan; Jeffrey Robbins; Joseph M Metzger
Journal:  Circ Res       Date:  2007-07-05       Impact factor: 17.367

9.  Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins.

Authors:  J van der Velden; Z Papp; R Zaremba; N M Boontje; J W de Jong; V J Owen; P B J Burton; P Goldmann; K Jaquet; G J M Stienen
Journal:  Cardiovasc Res       Date:  2003-01       Impact factor: 10.787

10.  The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy.

Authors:  Adam M Jacques; Natalia Briceno; Andrew E Messer; Clare E Gallon; Shapour Jalilzadeh; Edwin Garcia; Gaelle Kikonda-Kanda; Jennifer Goddard; Sian E Harding; Hugh Watkins; M Tomé Esteban; Victor T Tsang; William J McKenna; Steven B Marston
Journal:  Cardiovasc Res       Date:  2008-04-14       Impact factor: 10.787
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  5 in total

1.  Preconcentration and detection of the phosphorylated forms of cardiac troponin I in a cascade microchip by cationic isotachophoresis.

Authors:  Danny Bottenus; Mohammad Robiul Hossan; Yexin Ouyang; Wen-Ji Dong; Prashanta Dutta; Cornelius F Ivory
Journal:  Lab Chip       Date:  2011-09-21       Impact factor: 6.799

2.  Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.

Authors:  Martina Beck; George Komis; Jens Müller; Diedrik Menzel; Jozef Samaj
Journal:  Plant Cell       Date:  2010-03-09       Impact factor: 11.277

3.  10,000-fold concentration increase of the biomarker cardiac troponin I in a reducing union microfluidic chip using cationic isotachophoresis.

Authors:  Danny Bottenus; Talukder Zaki Jubery; Yexin Ouyang; Wen-Ji Dong; Prashanta Dutta; Cornelius F Ivory
Journal:  Lab Chip       Date:  2011-03-07       Impact factor: 6.799

Review 4.  Overview: the maturing of proteomics in cardiovascular research.

Authors:  Jennifer E Van Eyk
Journal:  Circ Res       Date:  2011-02-18       Impact factor: 17.367

5.  10,000-fold concentration increase in proteins in a cascade microchip using anionic ITP by a 3-D numerical simulation with experimental results.

Authors:  Danny Bottenus; Talukder Zaki Jubery; Prashanta Dutta; Cornelius F Ivory
Journal:  Electrophoresis       Date:  2011-02-10       Impact factor: 3.535
  5 in total

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