Literature DB >> 19171012

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

Merrin E Rutherford1, John D Dockerty, Momodou Jasseh, Stephen R C Howie, Peter Herbison, David J Jeffries, Kim Mulholland, Richard A Adegbola, Philip C Hill.   

Abstract

OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation.
METHODS: Case-control study in a population under demographic surveillance. Cases (n = 141) were children under five who died. Each was age and sex-matched to five controls (n = 705). Information was gathered by interviewing primary caregivers.
RESULTS: All but one of the interventions - whether the mother had received tetanus toxoid during pregnancy - were protective against child mortality after multivariate analysis. Having a trained person assisting at child birth (OR 0.2 95% CI 0.1-0.4), receiving all vaccinations by 9 months of age (OR 0.1; 95% CI 0.01-0.3), being breastfed for more than 12 months (Children breastfed between 13 and 24 months OR 0.1 95% CI 0.03-0.3, more than 25 months OR 0.1 95% CI 0.01-0.5) and receiving vitamin A supplementation at or after 6 months of age (OR 0.05; 95% CI 0.01-0.2) were protective against child death.
CONCLUSIONS: This study confirms the value of at least four available interventions in the prevention of under-five death in The Gambia. It is now important to identify those who are not receiving them and why, and to intervene to improve coverage across the population.

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Year:  2009        PMID: 19171012     DOI: 10.1111/j.1365-3156.2008.02204.x

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  8 in total

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6.  Under-five mortality in The Gambia: Comparison of the results of the first demographic and health survey with those from existing inquiries.

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7.  Adverse events following immunization reporting and impact on immunization services in informal settlements in Nairobi, Kenya: a prospective mixed-methods study.

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8.  Achieving comprehensive childhood immunization: an analysis of obstacles and opportunities in The Gambia.

Authors:  Sarah Payne; John Townend; Momodou Jasseh; Yamundow Lowe Jallow; Beate Kampmann
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  8 in total

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