Literature DB >> 19170106

Correlates and mediators of functional disability in obsessive-compulsive disorder.

Eric A Storch1, Jonathan S Abramowitz, Mary Keeley.   

Abstract

BACKGROUND: This study examined factors associated with obsessive-compulsive disorder (OCD) related functional disability in 87 treatment-seeking adults with OCD.
METHODS: A trained evaluator administered the Yale-Brown Obsessive-Compulsive Scale and Brown Assessment of Beliefs Scale. Patients completed the Sheehan Disability Scale, Obsessive-Compulsive Inventory-Revised, Interpretation of Intrusions Inventory, Thought-Action Fusion Scale, Beck Depression Inventory Second Edition, and State Trait Anxiety Inventory-Trait Version.
RESULTS: Results indicated that OCD symptoms, anxiety, depression, and the tendency to misinterpret the significance of intrusive thoughts were related to functional disability. Two variables-depressive symptoms and the extent to which a patient attempts to resist and is able to control OCD symptoms-emerged as unique predictors of functional disability. Mediational analyses indicated that both of these variables fully mediated the relationship between OCD-related distress and functional disability.
CONCLUSIONS: Results are discussed in terms of predictors of functional disability in OCD and in terms of implications for assessment and treatment.

Entities:  

Mesh:

Year:  2009        PMID: 19170106     DOI: 10.1002/da.20481

Source DB:  PubMed          Journal:  Depress Anxiety        ISSN: 1091-4269            Impact factor:   6.505


  10 in total

1.  Understudied clinical dimensions in pediatric obsessive compulsive disorder.

Authors:  Adam B Lewin; Nicole Caporino; Tanya K Murphy; Gary R Geffken; Eric A Storch
Journal:  Child Psychiatry Hum Dev       Date:  2010-12

2.  Targeted Family Intervention for Complex Cases of Pediatric Obsessive-Compulsive Disorder: A Randomized Controlled Trial.

Authors:  Tara S Peris; Michelle S Rozenman; Catherine A Sugar; James T McCracken; John Piacentini
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2017-10-14       Impact factor: 8.829

3.  Optimizing Obsessive-Compulsive Symptom Measurement With the Yale-Brown Obsessive-Compulsive Scales-Second Edition.

Authors:  Gregory S Vogt; Michelle Avendaño-Ortega; Sophie C Schneider; Wayne K Goodman; Eric A Storch
Journal:  J Psychiatr Pract       Date:  2022-07-01       Impact factor: 1.841

4.  Exploring Association Between Serotonin and Neurogenesis Related Genes in Obsessive-Compulsive Disorder in Chinese Han People: Promising Association Between DMRT2, miR-30a-5p, and Early-Onset Patients.

Authors:  Miaohan Deng; Yuan Wang; Shunying Yu; Qing Fan; Jianyin Qiu; Zhen Wang; Zeping Xiao
Journal:  Front Psychiatry       Date:  2022-05-13       Impact factor: 5.435

5.  Cluster analysis of psychiatric profile, its correlates, and using mental health services among the young people aged 15-34: findings from the first phase of Iranian youth cohort in Ravansar.

Authors:  Habibolah Khazaie; Farid Najafi; Behrooz Hamzeh; Azita Chehri; Afarin Rahimi-Movaghar; Masoumeh Amin-Esmaeili; Mehdi Moradi-Nazar; Ali Zakiei; Saeid Komasi; Yahya Pasdar
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2018-08-25       Impact factor: 4.328

6.  Eating disorder severity and functional impairment: moderating effects of illness duration in a clinical sample.

Authors:  Annika Helgadóttir Davidsen; William T Hoyt; Stig Poulsen; Mette Waaddegaard; Marianne Lau
Journal:  Eat Weight Disord       Date:  2016-09-22       Impact factor: 4.652

Review 7.  Patient-reported outcomes in obsessive-compulsive disorder.

Authors:  Mythily Subramaniam; Pauline Soh; Clarissa Ong; Lee Seng Esmond Seow; Louisa Picco; Janhavi Ajit Vaingankar; Siow Ann Chong
Journal:  Dialogues Clin Neurosci       Date:  2014-06       Impact factor: 5.986

8.  Do polygenic risk and stressful life events predict pharmacological treatment response in obsessive compulsive disorder? A gene-environment interaction approach.

Authors:  María Alemany-Navarro; Javier Costas; Eva Real; Cinto Segalàs; Sara Bertolín; Laura Domènech; Raquel Rabionet; Ángel Carracedo; Jose M Menchón; Pino Alonso
Journal:  Transl Psychiatry       Date:  2019-02-04       Impact factor: 6.222

9.  Evidence-based pharmacotherapy for pediatric obsessive-compulsive disorder and chronic tic disorders.

Authors:  Alessandro S De Nadai; Eric A Storch; Joseph F McGuire; Adam B Lewin; Tanya K Murphy
Journal:  J Cent Nerv Syst Dis       Date:  2011-06-01

10.  Metacognitive beliefs mediate the relationship between anxiety sensitivity and traits of obsessive-compulsive symptoms.

Authors:  Roberto Gutierrez; Tulsi Hirani; Leo Curtis; Amanda K Ludlow
Journal:  BMC Psychol       Date:  2020-04-26
  10 in total

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