| Literature DB >> 19169768 |
Ambar Khaira1, Bala Krishna Upadhyay1, Alok Sharma2, Prasenjit Das3, Sandeep Mahajan1, Govind Makhariya4, Amit K Dinda3, Sanjay K Agarwal1, Suresh C Tiwari1.
Abstract
The hepatitis B virus (HBV) is estimated to have infected about 350 million people worldwide, making it one of the most common human pathogens. Renal involvement is among its most common extra hepatic manifestations and usually manifests in the form of immune complex mediated glomerulopathy, such as membranous glomerulonephritis (MGN), membranoproliferative glomerulonephritis (MPGN), mesangioproliferative glomerulonephritis and immunoglobulin A (IgA) nephropathy. Occurrence of focal and segmental glomerular sclerosis (FSGS) with HBV infection is rare and only five cases have been reported earlier. We report two cases of hepatitis B associated FSGS. In both the cases, HBsAg was demonstrated in the renal tissue and both the cases showed response to treatment with lamivudine, thus indicating a possible causal association between the viral infection and occurrence of nephrotic syndrome.Entities:
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Year: 2009 PMID： 19169768 DOI： 10.1007/s10157-008-0124-8
Source DB: PubMed Journal: Clin Exp Nephrol ISSN： 1342-1751 Impact factor: 2.617