Literature DB >> 19168984

Nataxazole, a new benzoxazole derivative with antitumor activity produced by Streptomyces sp. Tü 6176.

Patricia S M Sommer1, Rosemary C Almeida, Kathrin Schneider, Winfried Beil, Roderich D Süssmuth, Hans-Peter Fiedler.   

Abstract

The new benzoxazole derivative nataxazole was isolated from Streptomyces sp. (strain Tü 6176). Nataxazole is related in structure to the potent antitumor compounds UK-1 and AJI9561 and showed similar strong growth inhibitory activity against various human tumor cell lines.

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Year:  2008        PMID: 19168984     DOI: 10.1038/ja.2008.97

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  11 in total

1.  Engineering Pseudochelin Production in Myxococcus xanthus.

Authors:  Juliane Korp; Lea Winand; Angela Sester; Markus Nett
Journal:  Appl Environ Microbiol       Date:  2018-10-30       Impact factor: 4.792

2.  Rh(I)-bisphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

Authors:  Claire M Filloux; Tomislav Rovis
Journal:  J Am Chem Soc       Date:  2014-12-29       Impact factor: 15.419

3.  Chemical Interaction among Termite-Associated Microbes.

Authors:  Emily Mevers; Thomas Chouvenc; Nan-Yao Su; Jon Clardy
Journal:  J Chem Ecol       Date:  2017-11-13       Impact factor: 2.626

4.  Exploring the biocombinatorial potential of benzoxazoles: generation of novel caboxamycin derivatives.

Authors:  Armando A Losada; Carmen Méndez; José A Salas; Carlos Olano
Journal:  Microb Cell Fact       Date:  2017-05-25       Impact factor: 5.328

5.  Caboxamycin biosynthesis pathway and identification of novel benzoxazoles produced by cross-talk in Streptomyces sp. NTK 937.

Authors:  Armando A Losada; Carolina Cano-Prieto; Raúl García-Salcedo; Alfredo F Braña; Carmen Méndez; José A Salas; Carlos Olano
Journal:  Microb Biotechnol       Date:  2017-04-18       Impact factor: 5.813

6.  Near-Complete Genome Sequences of Streptomyces sp. Strains AC1-42T and AC1-42W, Isolated from Bat Guano from Cabalyorisa Cave, Mabini, Pangasinan, Philippines.

Authors:  Marian P De Leon; A-Young Park; Andrew D Montecillo; Maria Auxilia T Siringan; Albert Remus R Rosana; Song-Gun Kim
Journal:  Microbiol Resour Announc       Date:  2018-08-23

7.  Anti-cancer and antimicrobial potential of five soil Streptomycetes: a metabolomics-based study.

Authors:  Nada Osama; Walid Bakeer; Mai Raslan; Hanan A Soliman; Usama Ramadan Abdelmohsen; Mohamed Sebak
Journal:  R Soc Open Sci       Date:  2022-02-09       Impact factor: 2.963

8.  Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin.

Authors:  Carlos Olano; Carolina Cano-Prieto; Armando A Losada; Alan T Bull; Michael Goodfellow; Hans-Peter Fiedler; Carmen Méndez; José A Salas
Journal:  Genome Announc       Date:  2014-07-03

9.  The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.

Authors:  Haigang Song; Cong Rao; Zixin Deng; Yi Yu; James H Naismith
Journal:  Angew Chem Int Ed Engl       Date:  2020-02-11       Impact factor: 15.336

10.  Biological activity of 3-(2-benzoxazol-5-yl)alanine derivatives.

Authors:  Katarzyna Guzow; Ewa Mulkiewicz; Michał Obuchowski; Wiesław Wiczk
Journal:  Amino Acids       Date:  2021-07-08       Impact factor: 3.520

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