Literature DB >> 19167926

The therapeutic helminth?

Derek M McKay1.   

Abstract

By definition, parasites harm their hosts. Yet substantial evidence from animal models of human disease support the hypothesis that infection with helminths can suppress the development of other maladies. Here, the view is presented that assessment of the immunophysiological response to helminths could identify that infection with specific parasites would be therapeutically useful (although many helminths could not fulfil this role) and lead to precise knowledge of the immune events following infection, to identify ways to intervene in disease processes (in the absence of infection per se) that can be used to treat, and eventually cure, inflammatory and autoimmune disease.

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Year:  2009        PMID: 19167926     DOI: 10.1016/j.pt.2008.11.008

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  24 in total

1.  Exacerbation of oxazolone colitis by infection with the helminth Hymenolepis diminuta: involvement of IL-5 and eosinophils.

Authors:  Arthur Wang; Maria Fernando; Gabriella Leung; Van Phan; David Smyth; Derek M McKay
Journal:  Am J Pathol       Date:  2010-10-29       Impact factor: 4.307

2.  Probiotic helminth administration in relapsing-remitting multiple sclerosis: a phase 1 study.

Authors:  J O Fleming; A Isaak; J E Lee; C C Luzzio; M D Carrithers; T D Cook; A S Field; J Boland; Z Fabry
Journal:  Mult Scler       Date:  2011-03-03       Impact factor: 6.312

3.  Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells.

Authors:  E J Klaver; T C T M van der Pouw Kraan; L C Laan; H Kringel; R D Cummings; G Bouma; G Kraal; I van Die
Journal:  Genes Immun       Date:  2015-05-21       Impact factor: 2.676

Review 4.  Trichinella spiralis: shaping the immune response.

Authors:  Natasa Ilic; Alisa Gruden-Movsesijan; Ljiljana Sofronic-Milosavljevic
Journal:  Immunol Res       Date:  2012-04       Impact factor: 2.829

Review 5.  Helminthes and insects: maladies or therapies.

Authors:  Nora L El-Tantawy
Journal:  Parasitol Res       Date:  2014-12-30       Impact factor: 2.289

Review 6.  Parasitic helminths: new weapons against immunological disorders.

Authors:  Yoshio Osada; Tamotsu Kanazawa
Journal:  J Biomed Biotechnol       Date:  2010-02-10

7.  Immuno-Modulatory Effect and Therapeutic Potential of Brugia malayi Cystatin in Experimentally Induced Arthritis.

Authors:  Ravi Shankar Prasad Yadav; Vishal Khatri; Nitin Amdare; Kalyan Goswami; V B Shivkumar; Nitin Gangane; Maryada Venkata Rami Reddy
Journal:  Indian J Clin Biochem       Date:  2015-07-23

8.  Cryopreserved Interleukin-4-Treated Macrophages Attenuate Murine Colitis in an Integrin β7 - Dependent Manner.

Authors:  Gabriella Leung; Björn Petri; José Luis Reyes; Arthur Wang; Jordan Iannuzzi; Derek M McKay
Journal:  Mol Med       Date:  2015-12-09       Impact factor: 6.354

Review 9.  Helminth genomics: The implications for human health.

Authors:  Paul J Brindley; Makedonka Mitreva; Elodie Ghedin; Sara Lustigman
Journal:  PLoS Negl Trop Dis       Date:  2009-10-26

10.  Infection with Hymenolepis diminuta is more effective than daily corticosteroids in blocking chemically induced colitis in mice.

Authors:  Alexandra Melon; Arthur Wang; Van Phan; Derek M McKay
Journal:  J Biomed Biotechnol       Date:  2010
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