Literature DB >> 19167220

Synthesis and antimicrobial activity of some new pyrazole derivatives containing a ferrocene unit.

Ivan Damljanović1, Mirjana Vukićević, Niko Radulović, Radosav Palić, Ernst Ellmerer, Zoran Ratković, Milan D Joksović, Rastko D Vukićević.   

Abstract

A series of new imines and amines have been synthesized by condensation of 1H-3-ferrocenyl-1-phenylpyrazole-4-carboxaldehyde with the corresponding amines, followed by reduction with sodium borohydride. The synthesized compounds have been screened for their in vitro antimicrobial activity against 11 bacteria and three fungal/yeast strains, using disc diffusion and broth microdilution susceptibility assays. They have shown a wide range of activities, from completely inactive to the highly active compounds.

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Year:  2009        PMID: 19167220     DOI: 10.1016/j.bmcl.2009.01.006

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  7 in total

1.  A novel pseudo six-component synthesis of functionalized pyrazoles in ethanol by cascade reaction.

Authors:  Atieh Rezvanian; Maedeh Babashah; Maryam Anafcheh
Journal:  Mol Divers       Date:  2019-01-11       Impact factor: 2.943

2.  Urea/thiourea: efficient, inexpensive and reusable catalysts for the synthesis of pyrazole derivatives with 2-iminothiazolidin-4-one and 2,4-thiazolidinediones under solvent-free conditions.

Authors:  Veera Swamy Konkala; Pramod Kumar Dubey
Journal:  Mol Divers       Date:  2017-01-04       Impact factor: 2.943

3.  Indium triflate promoted one-pot multicomponent synthesis of structurally diverse 3-amino-imidazo[1,2-a]pyridines.

Authors:  Suman Swami; Arunava Agarwala; Rahul Shrivastava
Journal:  Mol Divers       Date:  2016-09-26       Impact factor: 2.943

4.  Synthesis, characterization, and antimicrobial evaluation of a small library of ferrocene-containing acetoacetates and phenyl analogs: the discovery of a potent anticandidal agent.

Authors:  Niko S Radulović; Marko Z Mladenović; Zorica Stojanović-Radić; Goran A Bogdanović; Dragana Stevanović; Rastko D Vukićević
Journal:  Mol Divers       Date:  2014-03-13       Impact factor: 2.943

5.  Synthesis, Biological Evaluation, and Molecular Modeling Studies of 1-Aryl-1H-pyrazole-Fused Curcumin Analogues as Anticancer Agents.

Authors:  Nam Q H Doan; Ngan T K Nguyen; Vu B Duong; Ha T T Nguyen; Long B Vong; Diem N Duong; Nguyet-Thu T Nguyen; Tuyen L T Nguyen; Tuoi T H Do; Tuyen N Truong
Journal:  ACS Omega       Date:  2022-09-16

6.  Synthesis, characterization, and antimicrobial evaluation of carbostyril derivatives of 1H-pyrazole.

Authors:  Nilesh J Thumar; Manish P Patel
Journal:  Saudi Pharm J       Date:  2011-02-03       Impact factor: 4.330

7.  Synthesis, Characterization, and Electrochemistry of Diferrocenyl β-Diketones, -Diketonates, and Pyrazoles.

Authors:  Steve W Lehrich; Julia Mahrholdt; Marcus Korb; Alexander Hildebrandt; Jannie C Swarts; Heinrich Lang
Journal:  Molecules       Date:  2020-09-29       Impact factor: 4.411

  7 in total

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