Literature DB >> 19162486

Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.

Angela Bassoli1, Gigliola Borgonovo, Sara Caimi, Leonardo Scaglioni, Gabriella Morini, Aniello Schiano Moriello, Vincenzo Di Marzo, Luciano De Petrocellis.   

Abstract

Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the cloned TRPA1 channel when expressed in an heterologous cell system and are therefore suggested to be responsible for the chemesthetic properties of this plant.

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Year:  2008        PMID： 19162486     DOI： 10.1016/j.bmc.2008.12.057

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  13 in total

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Review 5.  A review on bioactivities of perilla: progress in research on the functions of perilla as medicine and food.

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Journal:  Evid Based Complement Alternat Med       Date:  2017-05-31       Impact factor: 2.629

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Authors:  Giuseppina Chianese; Ernesto Fattorusso; Masteria Yunovilsa Putra; Barbara Calcinai; Giorgio Bavestrello; Aniello Schiano Moriello; Luciano De Petrocellis; Vincenzo Di Marzo; Orazio Taglialatela-Scafati
Journal:  Mar Drugs       Date:  2012-11-02       Impact factor: 5.118

9.  Inhibition of Proinflammatory Cytokine Generation in Lung Inflammation by the Leaves of Perilla frutescens and Its Constituents.

Authors:  Hun Jai Lim; Kyeong Wan Woo; Kang Ro Lee; Sang Kook Lee; Hyun Pyo Kim
Journal:  Biomol Ther (Seoul)       Date:  2014-01       Impact factor: 4.634

10.  Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.

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Journal:  Molecules       Date:  2015-10-16       Impact factor: 4.411
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