PURPOSE: To investigate ultrashort TE spectroscopic imaging (UTESI) of short T2 tissues in the musculoskeletal (MSK) system. MATERIALS AND METHODS: Ultrashort TE pulse sequence is able to detect rapidly decaying signals from tissues with a short T2 relaxation time. Here a time efficient spectroscopic imaging technique based on a multiecho interleaved variable TE UTE acquisition is proposed for high-resolution spectroscopic imaging of the short T2 tissues in the MSK system. The projections were interleaved into multiple groups with the data for each group being collected with progressively increasing TEs. The small number of projections in each group sparsely but uniformly sampled k-space. Spectroscopic images were generated through Fourier transformation of the time domain images at variable TEs. T2* was quantified through exponential fitting of the time domain images or line shape fitting of the magnitude spectrum. The feasibility of this technique was demonstrated in volunteer and cadaveric specimen studies on a clinical 3T scanner. RESULTS: UTESI was applied to six cadaveric specimens and four human volunteers. High spatial resolution and contrast images were generated for the deep radial and calcified layers of articular cartilage, menisci, ligaments, tendons, and entheses, respectively. Line shape fitting of the UTESI magnitude spectroscopic images show a short T2* of 1.34 +/- 0.56 msec, 4.19 +/- 0.68 msec, 3.26 +/- 0.34 msec, 1.96 +/- 0.47 msec, and 4.21 +/- 0.38 msec, respectively. CONCLUSION: UTESI is a time-efficient method to image and characterize the short T2 tissues in the MSK system with high spatial resolution and high contrast.
PURPOSE: To investigate ultrashort TE spectroscopic imaging (UTESI) of short T2 tissues in the musculoskeletal (MSK) system. MATERIALS AND METHODS: Ultrashort TE pulse sequence is able to detect rapidly decaying signals from tissues with a short T2 relaxation time. Here a time efficient spectroscopic imaging technique based on a multiecho interleaved variable TE UTE acquisition is proposed for high-resolution spectroscopic imaging of the short T2 tissues in the MSK system. The projections were interleaved into multiple groups with the data for each group being collected with progressively increasing TEs. The small number of projections in each group sparsely but uniformly sampled k-space. Spectroscopic images were generated through Fourier transformation of the time domain images at variable TEs. T2* was quantified through exponential fitting of the time domain images or line shape fitting of the magnitude spectrum. The feasibility of this technique was demonstrated in volunteer and cadaveric specimen studies on a clinical 3T scanner. RESULTS: UTESI was applied to six cadaveric specimens and four human volunteers. High spatial resolution and contrast images were generated for the deep radial and calcified layers of articular cartilage, menisci, ligaments, tendons, and entheses, respectively. Line shape fitting of the UTESI magnitude spectroscopic images show a short T2* of 1.34 +/- 0.56 msec, 4.19 +/- 0.68 msec, 3.26 +/- 0.34 msec, 1.96 +/- 0.47 msec, and 4.21 +/- 0.38 msec, respectively. CONCLUSION: UTESI is a time-efficient method to image and characterize the short T2 tissues in the MSK system with high spatial resolution and high contrast.
Authors: Ja-Young Choi; Reni Biswas; Won C Bae; Robert Healey; Michael Im; Sheronda Statum; Eric Y Chang; Jiang Du; Graeme M Bydder; Darryl D'Lima; Christine B Chung Journal: Radiology Date: 2016-02-01 Impact factor: 11.105
Authors: Constance R Chu; Ashley A Williams; Robin V West; Yongxian Qian; Freddie H Fu; Bao H Do; Stephen Bruno Journal: Am J Sports Med Date: 2014-05-08 Impact factor: 6.202