Literature DB >> 1915866

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the Mr deduced from the cDNA sequence and the purified enzyme.

L Alvarez1, M Asunción, F Corrales, M A Pajares, J M Mato.   

Abstract

A 3 kb cDNA coding for rat liver S-adenosylmethionine (AdoMet) synthetase has been isolated. The Mr of the protein has been unequivocally determined by cDNA sequencing and enzyme purification on a thiopropyl-Sepharose column. The length of the mRNA 5' non-coding region has been defined by primer-extension analysis. The rat liver cloned cDNA has been also used to detect S-adenosylmethionine synthetase mRNA in human liver.

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Year:  1991        PMID： 1915866     DOI： 10.1016/0014-5793(91)81245-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  13 in total

1.  Methionine adenosyltransferase alpha-helix structure unfolds at lower temperatures than beta-sheet: a 2D-IR study.

Authors:  Ibon Iloro; Rosana Chehín; Félix M Goñi; María A Pajares; José-Luis R Arrondo
Journal:  Biophys J       Date:  2004-06       Impact factor: 4.033

2.  Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation.

Authors:  S C Lu; L Alvarez; Z Z Huang; L Chen; W An; F J Corrales; M A Avila; G Kanel; J M Mato
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-24       Impact factor: 11.205

3.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

4.  Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes.

Authors:  Miguel Delgado; Francisco Garrido; Juliana Pérez-Miguelsanz; María Pacheco; Teresa Partearroyo; Dolores Pérez-Sala; María Angeles Pajares
Journal:  Antioxid Redox Signal       Date:  2014-01-03       Impact factor: 8.401

5.  Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase. Identification of a cysteine residue critical for the oligomeric state.

Authors:  J Mingorance; L Alvarez; E Sánchez-Góngora; J M Mato; M A Pajares
Journal:  Biochem J       Date:  1996-05-01       Impact factor: 3.857

6.  Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA.

Authors:  E Sánchez-Góngora; J G Pastorino; L Alvarez; M A Pajares; C García; J R Viña; J M Mato; J L Farber
Journal:  Biochem J       Date:  1996-11-01       Impact factor: 3.857

7.  Effect of ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats.

Authors:  C M Rodríguez-Ortigosa; R N Cincu; S Sanz; F Ruiz; J Quiroga; J Prieto
Journal:  Gut       Date:  2002-05       Impact factor: 23.059

8.  eth-1, the Neurospora crassa locus encoding S-adenosylmethionine synthetase: molecular cloning, sequence analysis and in vivo overexpression.

Authors:  M R Mautino; J L Barra; A L Rosa
Journal:  Genetics       Date:  1996-03       Impact factor: 4.562

9.  Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies.

Authors:  L Alvarez; F Corrales; A Martín-Duce; J M Mato
Journal:  Biochem J       Date:  1993-07-15       Impact factor: 3.857

10.  Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms.

Authors:  L Alvarez; J Mingorance; M A Pajares; J M Mato
Journal:  Biochem J       Date:  1994-07-15       Impact factor: 3.857
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