| Literature DB >> 19158603 |
Candace Y W Lee1, Hsiao Lieu, John C Burnett.
Abstract
Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19158603 PMCID: PMC3129707 DOI: 10.2310/JIM.0b013e3181946fb2
Source DB: PubMed Journal: J Investig Med ISSN: 1081-5589 Impact factor: 2.895