PURPOSE: To report 2 cases of exogenous Candida glabrata endophthalmitis after penetrating keratoplasty in recipients of corneas from the same donor transplanted on the same day. METHODS: Case reports with ophthalmologic, electron microscopic, and microbiological findings including fungal strain analysis. RESULTS: Two patients developed fungal keratitis and endophthalmitis caused by the same C. glabrata strain within 1 day after penetrating keratoplasty of corneas from the same donor on the same day. Donor-to-host transmission was postulated when eye bank sterility checks were repeatedly negative. CONCLUSIONS: A short death-to-harvesting time, routine donor rim cultures, and respecting of a time interval before transplantation may provide an additional safety feature in dealing with corneal tissue from high-risk donors.
PURPOSE: To report 2 cases of exogenous Candida glabrata endophthalmitis after penetrating keratoplasty in recipients of corneas from the same donor transplanted on the same day. METHODS: Case reports with ophthalmologic, electron microscopic, and microbiological findings including fungal strain analysis. RESULTS: Two patients developed fungal keratitis and endophthalmitis caused by the same C. glabrata strain within 1 day after penetrating keratoplasty of corneas from the same donor on the same day. Donor-to-host transmission was postulated when eye bank sterility checks were repeatedly negative. CONCLUSIONS: A short death-to-harvesting time, routine donor rim cultures, and respecting of a time interval before transplantation may provide an additional safety feature in dealing with corneal tissue from high-risk donors.
Authors: Ying-Lien Chen; Alexandra Brand; Emma L Morrison; Fitz Gerald S Silao; Ursela G Bigol; Fedelino F Malbas; Jeniel E Nett; David R Andes; Norma V Solis; Scott G Filler; Anna Averette; Joseph Heitman Journal: Eukaryot Cell Date: 2011-04-29
Authors: Ying-Lien Chen; Jay H Konieczka; Deborah J Springer; Samantha E Bowen; Jing Zhang; Fitz Gerald S Silao; Alice Alma C Bungay; Ursela G Bigol; Marilou G Nicolas; Soman N Abraham; Dawn A Thompson; Aviv Regev; Joseph Heitman Journal: G3 (Bethesda) Date: 2012-06-01 Impact factor: 3.154
Authors: Grażyna Broniek; Ewa Langwińska-Wośko; Małgorzata Sybilska; Jerzy Szaflik; Jacek P Szaflik; Marta Wróblewska Journal: Arch Med Sci Date: 2016-03-31 Impact factor: 3.318