Literature DB >> 19156780

Receptor-mediated targeting of cathepsins in professional antigen presenting cells.

Ulrik Hillaert1, Martijn Verdoes, Bogdan I Florea, Athanasios Saragliadis, Anastasios Saragliadis, Kim L L Habets, Johan Kuiper, Serge Van Calenbergh, Ferry Ossendorp, Gijsbert A van der Marel, Christoph Driessen, Hermen S Overkleeft.   

Abstract

Tag for professionals: A fluorescently tagged clustered mannoside DCG-04 analogue (see structure) is designed and synthesized using a modular approach. Uptake of the probe in professional antigen presenting cells and subsequent labeling of cathepsins proceeded in a mannose-receptor dependent manner.

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Year:  2009        PMID： 19156780     DOI： 10.1002/anie.200805529

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  3 in total

1.  Organelle-specific activity-based protein profiling in living cells.

Authors:  Susan D Wiedner; Lindsey N Anderson; Natalie C Sadler; William B Chrisler; Vamsi K Kodali; Richard D Smith; Aaron T Wright
Journal:  Angew Chem Int Ed Engl       Date:  2014-02-06       Impact factor: 15.336

2.  Targeted delivery of antigen processing inhibitors to antigen presenting cells via mannose receptors.

Authors:  Benjamin M Chain; Alethea B Tabor; Eun-Ang Raiber; Calogero Tulone; Yanjing Zhang; Luisa Martinez-Pomares; Emily Steed; Anna M Sponaas; Jean Langhorne; Mahdad Noursadeghi
Journal:  ACS Chem Biol       Date:  2010-05-21       Impact factor: 5.100

3.  Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells.

Authors:  Julie D McIntosh; Margaret A Brimble; Anna E S Brooks; P Rod Dunbar; Renata Kowalczyk; Yusuke Tomabechi; Antony J Fairbanks
Journal:  Chem Sci       Date:  2015-05-19       Impact factor: 9.825
  3 in total

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