| Literature DB >> 19155029 |
Prem P Yadav1, Ranjani Maurya, Jayanta Sarkar, Ashish Arora, Sanjeev Kanojiya, Sudhir Sinha, M N Srivastava, Ram Raghubir.
Abstract
Three cassane diterpene hemiketals, caesalpinolide-C, caesalpinolide-D, caesalpinolide-E and one cassane furanoditerpene were isolated from Caesalpinia bonduc. The molecular structures were elucidated using NMR spectroscopy in combination with IR, UV and mass spectral data and relative stereochemistries were determined through ROESY correlation. The isolated compounds were tested for their antiproliferative activity against MCF-7 (breast adenocarcinoma), DU145 (prostate carcinoma), C33A (Cervical carcinoma) and Vero (African green monkey kidney fibroblast) cells.Entities:
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Year: 2009 PMID: 19155029 DOI: 10.1016/j.phytochem.2008.12.008
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072