| Literature DB >> 19154715 |
Lara C Skwarek1, Gabrielle L Boulianne.
Abstract
Phosphoinositides function as signaling precursors as well as regulators and scaffolds of signaling molecules required for important cellular processes such as membrane trafficking. Although a picture of the biochemical and cell biological functions of phosphoinositides is emerging, less is known about how these functions impact signaling on a broader scale during development. This review summarizes recent work on the role of phosphoinositides in developmental signaling and in a number of diseases and developmental disorders.Entities:
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Year: 2009 PMID: 19154715 DOI: 10.1016/j.devcel.2008.12.006
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270