Literature DB >> 19153119

The antidiabetic drug metformin: a pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy.

A Vazquez-Martin, C Oliveras-Ferraros, S del Barco, B Martin-Castillo, J A Menendez.   

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Year:  2009        PMID: 19153119     DOI: 10.1093/annonc/mdn758

Source DB:  PubMed          Journal:  Ann Oncol        ISSN: 0923-7534            Impact factor:   32.976


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  18 in total

1.  Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation.

Authors:  Hyung Gyun Kim; Tran Thi Hien; Eun Hee Han; Yong Pil Hwang; Jae Ho Choi; Keon Wook Kang; Kwang-il Kwon; Bong-Hee Kim; Sang Kyum Kim; Gye Yong Song; Tae Cheon Jeong; Hye Gwang Jeong
Journal:  Br J Pharmacol       Date:  2011-03       Impact factor: 8.739

2.  AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell.

Authors:  Gang Han; Hangjun Gong; Yidong Wang; Shaowen Guo; Kun Liu
Journal:  Cancer Biol Ther       Date:  2015       Impact factor: 4.742

Review 3.  Chemoprevention of hormone receptor-negative breast cancer: new approaches needed.

Authors:  Iván P Uray; Powel H Brown
Journal:  Recent Results Cancer Res       Date:  2011

Review 4.  Metformin and cancer: new applications for an old drug.

Authors:  Taxiarchis V Kourelis; Robert D Siegel
Journal:  Med Oncol       Date:  2011-02-08       Impact factor: 3.064

5.  Sensitizing multi drug resistant Staphylococcus aureus isolated from surgical site infections to antimicrobials by efflux pump inhibitors.

Authors:  Amr A Baiomy; Ghada H Shaker; Hisham A Abbas
Journal:  Afr Health Sci       Date:  2020-12       Impact factor: 0.927

6.  Underactivation of the adiponectin-adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression.

Authors:  Nir Kleinmann; Wilhelmina C M Duivenvoorden; Sarah N Hopmans; Laura K Beatty; Shengjun Qiao; Daniel Gallino; Sarka Lhotak; Dean Daya; Athanasios Paschos; Richard C Austin; Jehonathan H Pinthus
Journal:  Clin Exp Metastasis       Date:  2013-10-05       Impact factor: 5.150

Review 7.  mTOR inhibitors and the anti-diabetic biguanide metformin: new insights into the molecular management of breast cancer resistance to the HER2 tyrosine kinase inhibitor lapatinib (Tykerb).

Authors:  Alejandro Vázquez-Martín; Cristina Oliveras-Ferraros; Sonia del Barco; Begoña Martín-Castillo; Javier A Menéndez
Journal:  Clin Transl Oncol       Date:  2009-07       Impact factor: 3.405

8.  Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency.

Authors:  Alejandro Vazquez-Martin; Sílvia Cufi; Eugeni Lopez-Bonet; Bruna Corominas-Faja; Cristina Oliveras-Ferraros; Begoña Martin-Castillo; Javier A Menendez
Journal:  Sci Rep       Date:  2012-12-12       Impact factor: 4.379

9.  Gerosuppressant metformin: less is more.

Authors:  Javier A Menendez; Sílvia Cufí; Cristina Oliveras-Ferraros; Luciano Vellon; Jorge Joven; Alejandro Vazquez-Martin
Journal:  Aging (Albany NY)       Date:  2011-04       Impact factor: 5.682

Review 10.  Metformin for aging and cancer prevention.

Authors:  Vladimir N Anisimov
Journal:  Aging (Albany NY)       Date:  2010-11       Impact factor: 5.682

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