OBJECTIVES: To assess the prevalence of human papillomavirus (HPV) infection according to cervical cytologic status in northeastern Brazil; identify other risk factors for low- and high-grade squamous intraepithelial lesions (LSILs and HSILs); and identify the most prevalent HPV genotypes associated with the lesions. METHOD: Two cervical smears were collected from 250 women referred for cancer screening, one for cytologic examination and the other to test for the presence of HPV by PCR with genotyping by dot blot hybridization. RESULT: There were 110 healthy cervices, 82 LSILs, and 58 HSILs. The overall HPV prevalence was 48%, with higher rates for HSILs, and HPV-16 was the most prevalent type. Age, multiple sexual partners, type of HPV present, smoking, and early onset of sexual activity were risk factors for cervical lesions. CONCLUSION: Age, multiple sexual partners, and infection with HPV-16 increased the risk of having LSILs or HSILs. Early onset of sexual activity and smoking only increased the risk of having HSILs.
OBJECTIVES: To assess the prevalence of human papillomavirus (HPV) infection according to cervical cytologic status in northeastern Brazil; identify other risk factors for low- and high-grade squamous intraepithelial lesions (LSILs and HSILs); and identify the most prevalent HPV genotypes associated with the lesions. METHOD: Two cervical smears were collected from 250 women referred for cancer screening, one for cytologic examination and the other to test for the presence of HPV by PCR with genotyping by dot blot hybridization. RESULT: There were 110 healthy cervices, 82 LSILs, and 58 HSILs. The overall HPV prevalence was 48%, with higher rates for HSILs, and HPV-16 was the most prevalent type. Age, multiple sexual partners, type of HPV present, smoking, and early onset of sexual activity were risk factors for cervical lesions. CONCLUSION: Age, multiple sexual partners, and infection with HPV-16 increased the risk of having LSILs or HSILs. Early onset of sexual activity and smoking only increased the risk of having HSILs.
Authors: I G S S Serra; E D Araujo; G S Barros; F L S G Santos; R Q Gurgel; M V A Batista Journal: Epidemiol Infect Date: 2018-05-21 Impact factor: 4.434
Authors: L Golfetto; E V Alves; T R Martins; T C M Sincero; J B S Castro; C Dannebrock; J G Oliveira; J E Levi; A S C Onofre; M L Bazzo Journal: Braz J Med Biol Res Date: 2018-03-26 Impact factor: 2.590
Authors: Erika Galvão Lima; Diego Breno Soares de Lima; Cleine Aglacy Nunes Miranda; Valeska Santana de Sena Pereira; Jenner Chrystian Veríssimo de Azevedo; Josélio Maria Galvão de Araújo; Thales Allyrio Araújo de Medeiros Fernandes; Paulo Roberto Medeiros de Azevedo; José Veríssimo Fernandes Journal: ISRN Obstet Gynecol Date: 2013-03-31
Authors: Jv Fernandes; Mgf Carvalho; Taam de Fernandes; Jmg Araújo; Prm Azevedo; Jcv Azevedo; Rv Meissner Journal: Ann Med Health Sci Res Date: 2013-10
Authors: Toni Ricardo Martins; Cristina Mendes de Oliveira; Luciana Reis Rosa; Cristiane de Campos Centrone; Célia Luiza Regina Rodrigues; Luisa Lina Villa; José Eduardo Levi Journal: Virol J Date: 2016-08-12 Impact factor: 4.099