Literature DB >> 19149791

Short QT interval: A novel predictor of androgen abuse in strength trained athletes.

Mohammad Ali Babaee Bigi1, Amir Aslani, Arsalan Aslani.   

Abstract

OBJECTIVES: To find the relationship between anabolic androgenic steroids (AAS) using and QT interval in athletes.
METHODS: Between January 1, 2005 and May 31, 2007, we examined QTc interval duration in 165 consecutive male professional bodybuilders [age: 32.1 +/- 4.6 years]. Of these, 79 were AAS users. The control group included 90 sedentary age and gender matched subjects [none of them were AAS users].
RESULTS: The QTc interval of AAS abusing bodybuilders was significantly shorter compared with QTc interval in AAS-free bodybuilders and control group. Short QTc interval (< or =380 ms) was an independent predictor of AAS abusing in the multivariate analysis.
CONCLUSIONS: To the best of our knowledge, there is no published report regarding electrocardiographic diagnosis and screening of AAS abusing athletes. In the present study, we present an easy and applicable method to screen and diagnose AAS abusing among professional bodybuilders. In the presence of QTc interval < or = 380 ms in a bodybuilder, one would predict AAS abusing with 83% sensitivity and 88% specificity.

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Year:  2009        PMID: 19149791      PMCID: PMC6932133          DOI: 10.1111/j.1542-474X.2008.00271.x

Source DB:  PubMed          Journal:  Ann Noninvasive Electrocardiol        ISSN: 1082-720X            Impact factor:   1.468


  13 in total

1.  Cardiovascular effects of androgenic anabolic steroids in male bodybuilders determined by tissue Doppler imaging.

Authors:  Stéphane Nottin; Long-Dang Nguyen; Mohamed Terbah; Philippe Obert
Journal:  Am J Cardiol       Date:  2006-02-02       Impact factor: 2.778

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Journal:  Circulation       Date:  1977-04       Impact factor: 29.690

3.  Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings.

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Journal:  Am J Cardiol       Date:  1986-02-15       Impact factor: 2.778

4.  Effects of sex hormones on ECG parameters and expression of cardiac ion channels in dogs.

Authors:  L Fülöp; T Bányász; G Szabó; I B Tóth; T Bíró; I Lôrincz; A Balogh; K Petô; I Mikó; P P Nánási
Journal:  Acta Physiol (Oxf)       Date:  2006 Nov-Dec       Impact factor: 6.311

5.  Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.

Authors:  D J Sahn; A DeMaria; J Kisslo; A Weyman
Journal:  Circulation       Date:  1978-12       Impact factor: 29.690

6.  QT interval and QT dispersion in endurance athletes and in power athletes using large doses of anabolic steroids.

Authors:  A Stolt; T Karila; M Viitasalo; M Mäntysaari; U M Kujala; J Karjalainen
Journal:  Am J Cardiol       Date:  1999-08-01       Impact factor: 2.778

Review 7.  Anabolic steroids: a review for the clinician.

Authors:  Eric C Kutscher; Brian C Lund; Paul J Perry
Journal:  Sports Med       Date:  2002       Impact factor: 11.136

Review 8.  The cardiac toxicity of anabolic steroids.

Authors:  M L Sullivan; C M Martinez; P Gennis; E J Gallagher
Journal:  Prog Cardiovasc Dis       Date:  1998 Jul-Aug       Impact factor: 8.194

9.  Estimated prevalence of anabolic steroid use among male high school seniors.

Authors:  W E Buckley; C E Yesalis; K E Friedl; W A Anderson; A L Streit; J E Wright
Journal:  JAMA       Date:  1988-12-16       Impact factor: 56.272

10.  In vivo androgen treatment shortens the QT interval and increases the densities of inward and delayed rectifier potassium currents in orchiectomized male rabbits.

Authors:  Xiao-Ke Liu; Alexander Katchman; Bernard H Whitfield; Grace Wan; Einsley M Janowski; Raymond L Woosley; Steven N Ebert
Journal:  Cardiovasc Res       Date:  2003-01       Impact factor: 10.787

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  7 in total

1.  Short QT interval linked to androgen misuse: wider significance and possible basis.

Authors:  Jules C Hancox; Stéphanie C Choisy; Andrew F James
Journal:  Ann Noninvasive Electrocardiol       Date:  2009-07       Impact factor: 1.468

2.  The Effect of Chronic Anabolic-Androgenic Steroid Use on Tp-E Interval, Tp-E/Qt Ratio, and Tp-E/Qtc Ratio in Male Bodybuilders.

Authors:  Elnur Alizade; Anıl Avcı; Serdar Fidan; Mustafa Tabakçı; Mustafa Bulut; Regayip Zehir; Zeki Simsek; Mert Evlice; Uğur Arslantaş; Hakan Çakır; Mehmet Yunus Emiroglu; Mustafa Akçakoyun
Journal:  Ann Noninvasive Electrocardiol       Date:  2015-01-28       Impact factor: 1.468

Review 3.  Testosterone, myocardial function, and mortality.

Authors:  Vittorio Emanuele Bianchi
Journal:  Heart Fail Rev       Date:  2018-09       Impact factor: 4.214

Review 4.  Anabolic steroids and cardiovascular risk.

Authors:  Peter Angell; Neil Chester; Danny Green; John Somauroo; Greg Whyte; Keith George
Journal:  Sports Med       Date:  2012-02-01       Impact factor: 11.136

5.  Ventricular structure, function, and focal fibrosis in anabolic steroid users: a CMR study.

Authors:  Peter J Angell; Tevfik F Ismail; Andrew Jabbour; Gillian Smith; Annette Dahl; Ricardo Wage; Greg Whyte; Daniel J Green; Sanjay Prasad; Keith George
Journal:  Eur J Appl Physiol       Date:  2014-01-28       Impact factor: 3.078

6.  The Validity of Adding ECG to the Preparticipation Screening of Athletes An Evidence Based Literature Review.

Authors:  A Alattar; N Maffulli
Journal:  Transl Med UniSa       Date:  2014-12-19

7.  [Study of unexpectedly detected repolarization in a group of black athletes].

Authors:  Oussama Ben Rejeb; Hela Ghali; Yosra Messaoudi; Anissa Gharbi; Imen Bouhlel; Samia Ernez; Abdallah Mahdhaoui; Gouider Jeridi
Journal:  Pan Afr Med J       Date:  2019-06-14
  7 in total

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