Literature DB >> 19149661

Oncomirs: from tumor biology to molecularly targeted anticancer strategies.

Simone Mocellin1, Sandro Pasquali, Pierluigi Pilati.   

Abstract

Deregulation of microRNA (miRNA) promotes carcinogenesis, as these molecules can act as oncogenes or tumor suppressor genes. Here we provide an overview of miRNA biology, discuss the most recent findings on miRNA and cancer development/progression, and report on how tumor-related miRNAs (oncomirs) are being used to develop novel cancer specific therapeutic approaches.

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Year:  2009        PMID： 19149661     DOI： 10.2174/138955709787001802

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  21 in total

1.  Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells.

Authors:  Tissa T Manavalan; Yun Teng; Savitri N Appana; Susmita Datta; Theodore S Kalbfleisch; Yong Li; Carolyn M Klinge
Journal:  Cancer Lett       Date:  2011-09-10       Impact factor: 8.679

2.  MiR-145 regulates cancer stem-like properties and epithelial-to-mesenchymal transition in lung adenocarcinoma-initiating cells.

Authors:  Jingwen Hu; Mantang Qiu; Feng Jiang; Shuai Zhang; Xin Yang; Jie Wang; Lin Xu; Rong Yin
Journal:  Tumour Biol       Date:  2014-06-06

3.  The microRNA spectrum in 12 body fluids.

Authors:  Jessica A Weber; David H Baxter; Shile Zhang; David Y Huang; Kuo How Huang; Ming Jen Lee; David J Galas; Kai Wang
Journal:  Clin Chem       Date:  2010-09-16       Impact factor: 8.327

4.  Expression profile of MicroRNAs in young stroke patients.

Authors:  Kay Sin Tan; Arunmozhiarasi Armugam; Sugunavathi Sepramaniam; Kai Ying Lim; Karolina Dwi Setyowati; Chee Woon Wang; Kandiah Jeyaseelan
Journal:  PLoS One       Date:  2009-11-02       Impact factor: 3.240

5.  microRNA expression patterns reveal differential expression of target genes with age.

Authors:  Nicole Noren Hooten; Kotb Abdelmohsen; Myriam Gorospe; Ngozi Ejiogu; Alan B Zonderman; Michele K Evans
Journal:  PLoS One       Date:  2010-05-20       Impact factor: 3.240

Review 6.  Epigenetics in the placenta.

Authors:  Matthew A Maccani; Carmen J Marsit
Journal:  Am J Reprod Immunol       Date:  2009-08       Impact factor: 3.886

7.  Stroke-induced microRNAs: The potential therapeutic role for stroke.

Authors:  Ping Wu; Xialin Zuo; Aimin Ji
Journal:  Exp Ther Med       Date:  2012-01-31       Impact factor: 2.447

8.  Association between hsa-miR-34b/c rs4938723 T > C promoter polymorphism and cancer risk: a meta-analysis based on 6,036 cases and 6,204 controls.

Authors:  Tao Tao; Shuqiu Chen; Bin Xu; Chunhui Liu; Yiduo Wang; Yeqing Huang; Ming Chen
Journal:  Chin J Cancer Res       Date:  2014-06       Impact factor: 5.087

Review 9.  Novel functions for small RNA molecules.

Authors:  Chunxiang Zhang
Journal:  Curr Opin Mol Ther       Date:  2009-12

10.  miRandola: extracellular circulating microRNAs database.

Authors:  Francesco Russo; Sebastiano Di Bella; Giovanni Nigita; Valentina Macca; Alessandro Laganà; Rosalba Giugno; Alfredo Pulvirenti; Alfredo Ferro
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240
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