Literature DB >> 19149660

NF-kappaB: the inducible factors of HIV-1 transcription and their inhibitors.

Yu Mingyan1, Liu Xinyong, Erik De Clercq.   

Abstract

NF-kappaB (NF-kappaB), the transcription factors of HIV-1, play an important role in triggering HIV transcription. The inhibition of NF-kappaB activation and their signaling pathway offers a potential anti-HIV therapy strategy. This review reports the mode of action of NF-kappaB in triggering HIV-1 transcription and the status of the inhibitors.

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Year:  2009        PMID： 19149660     DOI： 10.2174/138955709787001677

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  13 in total

1.  Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.

Authors:  Marta J Gonzalez-Hernandez; Michael D Swanson; Rafael Contreras-Galindo; Sarah Cookinham; Steven R King; Richard J Noel; Mark H Kaplan; David M Markovitz
Journal:  J Virol       Date:  2012-05-16       Impact factor: 5.103

2.  Proline-proline-glutamic acid (PPE) protein Rv1168c of Mycobacterium tuberculosis augments transcription from HIV-1 long terminal repeat promoter.

Authors:  Khalid Hussain Bhat; Chinta Krishna Chaitanya; Nazia Parveen; Raja Varman; Sudip Ghosh; Sangita Mukhopadhyay
Journal:  J Biol Chem       Date:  2012-03-15       Impact factor: 5.157

Review 3.  HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research.

Authors:  Melissa J Churchill; Daniel J Cowley; Steve L Wesselingh; Paul R Gorry; Lachlan R Gray
Journal:  J Neurovirol       Date:  2014-07-25       Impact factor: 2.643

4.  Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C.

Authors:  Jessica M Mates; Surender B Kumar; Jose Bazan; Megan Mefford; Igor Voronkin; Samuel Handelman; Victor Mwapasa; William Ackerman; Daniel Janies; Jesse J Kwiek
Journal:  AIDS Res Hum Retroviruses       Date:  2013-08-12       Impact factor: 2.205

5.  Caveolin 1 inhibits HIV replication by transcriptional repression mediated through NF-κB.

Authors:  Xiao Mei Wang; Peter E Nadeau; Shanshan Lin; Jeffrey R Abbott; Ayalew Mergia
Journal:  J Virol       Date:  2011-03-23       Impact factor: 5.103

6.  Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65.

Authors:  Giuseppe Fiume; Eleonora Vecchio; Annamaria De Laurentiis; Francesca Trimboli; Camillo Palmieri; Antonio Pisano; Cristina Falcone; Marilena Pontoriero; Annalisa Rossi; Annarita Scialdone; Francesca Fasanella Masci; Giuseppe Scala; Ileana Quinto
Journal:  Nucleic Acids Res       Date:  2011-12-19       Impact factor: 16.971

Review 7.  Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.

Authors:  Evelyn M Kilareski; Sonia Shah; Michael R Nonnemacher; Brian Wigdahl
Journal:  Retrovirology       Date:  2009-12-23       Impact factor: 4.602

8.  Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network.

Authors:  Bi-Qing Li; Bing Niu; Lei Chen; Ze-Jun Wei; Tao Huang; Min Jiang; Jing Lu; Ming-Yue Zheng; Xiang-Yin Kong; Yu-Dong Cai
Journal:  PLoS One       Date:  2013-06-06       Impact factor: 3.240

Review 9.  Broad-spectrum antiviral agents.

Authors:  Jun-Da Zhu; Wen Meng; Xiao-Jia Wang; Hwa-Chain R Wang
Journal:  Front Microbiol       Date:  2015-05-22       Impact factor: 5.640

10.  Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events.

Authors:  Lyndsey R Buckner; Angela M Amedee; Hannah L Albritton; Pamela A Kozlowski; Nedra Lacour; Chris L McGowin; Danny J Schust; Alison J Quayle
Journal:  PLoS One       Date:  2016-01-05       Impact factor: 3.240
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