Literature DB >> 19148911

Spectral tuning of azobenzene photoswitches for biological applications.

Oleg Sadovski1, Andrew A Beharry, Fuzhong Zhang, G Andrew Woolley.   

Abstract

Longer switching wavelengths and good photochemical yields and stabilities of the cis isomers in reducing aqueous environments are achieved by introducing 2,2'-aminoalkyl substituents into 4,4'-diamido-substituted azobenzenes. The products are thus suitable for photocontrol of biomolecular structures in intracellular environments, such as switching between two peptide configurations (see picture).

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Year:  2009        PMID: 19148911     DOI: 10.1002/anie.200805013

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  35 in total

1.  Engineering light-regulated ion channels.

Authors:  Doris L Fortin; Timothy W Dunn; Richard H Kramer
Journal:  Cold Spring Harb Protoc       Date:  2011-06-01

2.  Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors.

Authors:  Ivan Tochitsky; Matthew R Banghart; Alexandre Mourot; Jennifer Z Yao; Benjamin Gaub; Richard H Kramer; Dirk Trauner
Journal:  Nat Chem       Date:  2012-01-10       Impact factor: 24.427

3.  Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.

Authors:  Alexandre Mourot; Christian Herold; Michael A Kienzler; Richard H Kramer
Journal:  Br J Pharmacol       Date:  2017-07-27       Impact factor: 8.739

4.  Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics.

Authors:  Yu-Ying Yang; Markus Grammel; Anuradha S Raghavan; Guillaume Charron; Howard C Hang
Journal:  Chem Biol       Date:  2010-11-24

5.  Development of a new photochromic ion channel blocker via azologization of fomocaine.

Authors:  Matthias Schoenberger; Arunas Damijonaitis; Zinan Zhang; Daniel Nagel; Dirk Trauner
Journal:  ACS Chem Neurosci       Date:  2014-06-05       Impact factor: 4.418

6.  Controlling the enzymatic activity of a restriction enzyme by light.

Authors:  Benno Schierling; Ann-Josée Noël; Wolfgang Wende; Le Thi Hien; Eugeny Volkov; Elena Kubareva; Tatiana Oretskaya; Michael Kokkinidis; Andreas Römpp; Bernhard Spengler; Alfred Pingoud
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-18       Impact factor: 11.205

7.  A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor.

Authors:  Michael A Kienzler; Andreas Reiner; Eric Trautman; Stan Yoo; Dirk Trauner; Ehud Y Isacoff
Journal:  J Am Chem Soc       Date:  2013-11-14       Impact factor: 15.419

8.  Tuning photochromic ion channel blockers.

Authors:  Alexandre Mourot; Michael A Kienzler; Matthew R Banghart; Timm Fehrentz; Florian M E Huber; Marco Stein; Richard H Kramer; Dirk Trauner
Journal:  ACS Chem Neurosci       Date:  2011-06-09       Impact factor: 4.418

9.  Photochromic potassium channel blockers: design and electrophysiological characterization.

Authors:  Alexandre Mourot; Timm Fehrentz; Richard H Kramer
Journal:  Methods Mol Biol       Date:  2013

10.  Using photons to manipulate enzyme inhibition by an azobenzene-modified nucleic acid probe.

Authors:  Youngmi Kim; Joseph A Phillips; Haipeng Liu; Huaizhi Kang; Weihong Tan
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-09       Impact factor: 11.205

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