| Literature DB >> 19148863 |
Sheng-Jun Dai1, Yan Ren, Li Shen, De-Wu Zhang.
Abstract
Two new alkaloids, named suspensine A (1) and (-)-7'-O-methylegenine (2), along with two known alkaloids, (-)-egenine (3) and (-)-bicuculline (4), were isolated from the ethanolic extract of the fruits of Forsythia suspensa. Their structures were established by means of chemical methods and spectroscopic analyses. In vitro, four alkaloids showed anti-inflammatory activities, with inhibition rates of release of beta-glucuronidase from polymorphonuclear leukocytes of rats being in the range 34.8%-39.6% at 10 microM.Entities:
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Year: 2009 PMID： 19148863 DOI： 10.1055/s-0028-1112204
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352