Literature DB >> 19148168

Chemical biologists gather in Heidelberg.

Maja Köhn1, Carsten Schultz.   

Abstract

Chemical biology is well defined at its core--chemistry helping to answer biological questions--yet the boundaries are rather fuzzy. What are the differences between chemical biology and pharmacology? Is intracellular imaging a branch of chemical biology, and what about screening libraries? At Chemical Biology 2008, held in Heidelberg in October, participants heard presentations covering all these topics and more.

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Year:  2009        PMID： 19148168     DOI： 10.1038/nchembio0209-66

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  18 in total

1.  Phototriggering of cell adhesion by caged cyclic RGD peptides.

Authors:  Svea Petersen; José María Alonso; Alexandre Specht; Portia Duodu; Maurice Goeldner; Aranzazu del Campo
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

2.  Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.

Authors:  Federico Bernal; Andrew F Tyler; Stanley J Korsmeyer; Loren D Walensky; Gregory L Verdine
Journal:  J Am Chem Soc       Date:  2007-02-07       Impact factor: 15.419

3.  Native chemical ligation at valine.

Authors:  Christian Haase; Heike Rohde; Oliver Seitz
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  Crystal structure and mechanism of a DNA (6-4) photolyase.

Authors:  Melanie J Maul; Thomas R M Barends; Andreas F Glas; Max J Cryle; Tatiana Domratcheva; Sabine Schneider; Ilme Schlichting; Thomas Carell
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

5.  Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.

Authors:  Markus Hafner; Anton Schmitz; Imke Grüne; Seergazhi G Srivatsan; Bianca Paul; Waldemar Kolanus; Thomas Quast; Elisabeth Kremmer; Inga Bauer; Michael Famulok
Journal:  Nature       Date:  2006-12-14       Impact factor: 49.962

6.  Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction.

Authors:  Christina Ludwig; Dirk Schwarzer; Henning D Mootz
Journal:  J Biol Chem       Date:  2008-07-14       Impact factor: 5.157

7.  Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells.

Authors:  Yuuta Fujikawa; Yasuteru Urano; Toru Komatsu; Kenjiro Hanaoka; Hirotatsu Kojima; Takuya Terai; Hideshi Inoue; Tetsuo Nagano
Journal:  J Am Chem Soc       Date:  2008-10-09       Impact factor: 15.419

8.  Global mapping of the topography and magnitude of proteolytic events in apoptosis.

Authors:  Melissa M Dix; Gabriel M Simon; Benjamin F Cravatt
Journal:  Cell       Date:  2008-08-22       Impact factor: 41.582

9.  Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells.

Authors:  Peter Varnai; Baskaran Thyagarajan; Tibor Rohacs; Tamas Balla
Journal:  J Cell Biol       Date:  2006-11-06       Impact factor: 10.539

10.  A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.

Authors:  S Rayter; R Elliott; J Travers; M G Rowlands; T B Richardson; K Boxall; K Jones; S Linardopoulos; P Workman; W Aherne; C J Lord; A Ashworth
Journal:  Oncogene       Date:  2007-08-13       Impact factor: 9.867
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