Literature DB >> 19147323

Endovascular treatment of ruptured abdominal aortic aneurysms in the United States (2001-2006): a significant survival benefit over open repair is independently associated with increased institutional volume.

James McPhee1, Mohammad H Eslami, Elias J Arous, Louis M Messina, Andres Schanzer.   

Abstract

OBJECTIVE: Endovascular aortic repair (EVAR) has gained wide acceptance for the elective treatment of abdominal aortic aneurysms (AAA), leading to interest in similar treatment of ruptured abdominal aortic aneurysms (RAAA). The purpose of this study was to evaluate national outcomes after EVAR for RAAA and to assess the effect of institutional volume metrics.
METHODS: The Nationwide Inpatient Sample was used to identify patients treated with open or EVAR for RAAA, 2001-2006. Procedure volume was determined for each institution categorizing hospitals as low-, medium-, and high-volume. The primary outcome was in-hospital mortality. Secondary outcomes related to resource utilization. Multivariable logistic regression models were used to determine independent predictors of EVAR usage and mortality.
RESULTS: From 2001 to 2006, an estimated 27,750 hospital discharges for RAAA occurred; 11.5% were treated with EVAR. EVAR utilization increased over time (5.9% in 2001 to 18.9% in 2006, P < .0001) while overall RAAA rates remained constant. EVAR had a lower overall in-hospital mortality than open repair (31.7% vs 40.7%, P < .0001), an effect which amplified when stratified by institutional volume. On multivariable regression, open repair independently predicted mortality (odds ratio [OR] 1.56; 95% confidence interval [CI] 1.29-1.89). EVAR usage for RAAA increased with age (>80 years) (OR 1.58; 95% CI 1.30-1.93), high elective EVAR volume (>40/y) vs medium (19-40/y) (OR 2.65; 95% CI 1.86-3.78) and low (<19/y) (OR 5.37; 95% CI 3.60-8.0). EVAR had a shorter length of stay (11.1 vs 13.8 days, P < .0001), higher discharges to home (65.1% vs 53.9%, P < .0001), and lower charges ($108,672 vs $114,784, P < .0001).
CONCLUSIONS: In the United States, for RAAA, EVAR had a lower postoperative mortality than open repair. Higher elective open repair as well as RAAA volume increased this mortality advantage for EVAR. These results support regionalization of RAAA repair to high volume centers whenever possible and a wider adoption of endovascular repair of RAAA nationwide.

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Year:  2009        PMID: 19147323     DOI: 10.1016/j.jvs.2008.11.002

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  18 in total

Review 1.  Current treatment strategies for ruptured abdominal aortic aneurysm.

Authors:  Andreas S Peters; Maani Hakimi; Philipp Erhart; Michael Keese; Thomas Schmitz-Rixen; Markus Wortmann; Moritz S Bischoff; Dittmar Böckler
Journal:  Langenbecks Arch Surg       Date:  2016-04-07       Impact factor: 3.445

2.  Open treatment versus endovascular repair for aortic abdominal aneurysm-keeping the balance.

Authors:  Wtgj Bos; T Cohen; G Vourliotakis; Mrhm van Sambeek; Elg Verhoeven
Journal:  Ann Vasc Dis       Date:  2009-12-14

Review 3.  Endovascular Treatment versus Open Repair for Abdominal Aortic Aneurysms: The Influence of Fitness in Decision Making.

Authors:  Konstnatinos G Moulakakis; Ilias Dalainas; John Kakisis; Spyridon Mylonas; Christos D Liapis
Journal:  Int J Angiol       Date:  2013-03

4.  Common iliac aneurysm rupture after previous aortic aneurysm resection.

Authors:  K J Mylankal; Z Baxter; E P Perry
Journal:  Ann Vasc Dis       Date:  2010-07-21

5.  Comparative effectiveness of endovascular versus open repair of ruptured abdominal aortic aneurysm in the Medicare population.

Authors:  Samuel T Edwards; Marc L Schermerhorn; A James O'Malley; Rodney P Bensley; Rob Hurks; Philip Cotterill; Bruce E Landon
Journal:  J Vasc Surg       Date:  2013-12-15       Impact factor: 4.268

Review 6.  Abdominal Aortic Aneurysm: Evolving Controversies and Uncertainties.

Authors:  Davide Carino; Timur P Sarac; Bulat A Ziganshin; John A Elefteriades
Journal:  Int J Angiol       Date:  2018-05-29

7.  Conversion to Open Repair from Emergency EVAR in a Patient with Ruptured AAA: Report of a Case.

Authors:  Toshiro Ito; Tetsuya Koyanagi; Nobuyoshi Kawaharada; Yoshihiko Kurimoto; Takeshi Uzuka; Mayuko Uehara; Takayuki Hagiwara; Yohsuke Yanase; Toshiyuki Maeda; Tetsuya Higami
Journal:  Ann Vasc Dis       Date:  2012-11-15

8.  Long-term survival and quality of life after open abdominal aortic aneurysm repair.

Authors:  Tim K Timmers; Joost A van Herwaarden; Gert-Jan de Borst; Frans L Moll; Luke P H Leenen
Journal:  World J Surg       Date:  2013-12       Impact factor: 3.352

9.  Derivation and validation of a practical risk score for prediction of mortality after open repair of ruptured abdominal aortic aneurysms in a US regional cohort and comparison to existing scoring systems.

Authors:  William P Robinson; Andres Schanzer; Youfu Li; Philip P Goodney; Brian W Nolan; Mohammad H Eslami; Jack L Cronenwett; Louis M Messina
Journal:  J Vasc Surg       Date:  2012-11-20       Impact factor: 4.268

10.  Risk factors and outcomes associated with acute kidney injury following ruptured abdominal aortic aneurysm.

Authors:  Ilana Kopolovic; Kim Simmonds; Shelley Duggan; Mark Ewanchuk; Daniel E Stollery; Sean M Bagshaw
Journal:  BMC Nephrol       Date:  2013-05-01       Impact factor: 2.388

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