OBJECTIVE: To investigate the success rate of proximal tubal occlusion with Essure devices in subfertile women with hydrosalpinges, and to observe the results of subsequent treatment with IVF. DESIGN: Prospective, single-arm, clinical study. SETTING: University hospital and teaching hospital. PATIENT(S): Ten women with uni- or bilateral hydrosalpinges prior to IVF. In all patients laparoscopy was felt to be contraindicated. INTERVENTION(S): Hysteroscopic placement of Essure devices in an office setting. MAIN OUTCOME MEASURE(S): Placement rate, successful proximal tubal occlusion, and pregnancy rate after IVF. RESULT(S): All patients had successful placement of the Essure devices without any complications. Proximal tubal occlusion was confirmed by hysterosalpingography in 9 out of 10 patients. A 40% ongoing pregnancy rate was achieved with 20% life births after one IVF cycle and/or frozen embryo transfer. CONCLUSION(S): Proximal occlusion of hydrosalpinges with Essure devices before IVF is a successful treatment for patients with a contraindication for salpingectomy. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
OBJECTIVE: To investigate the success rate of proximal tubal occlusion with Essure devices in subfertile women with hydrosalpinges, and to observe the results of subsequent treatment with IVF. DESIGN: Prospective, single-arm, clinical study. SETTING: University hospital and teaching hospital. PATIENT(S): Ten women with uni- or bilateral hydrosalpinges prior to IVF. In all patients laparoscopy was felt to be contraindicated. INTERVENTION(S): Hysteroscopic placement of Essure devices in an office setting. MAIN OUTCOME MEASURE(S): Placement rate, successful proximal tubal occlusion, and pregnancy rate after IVF. RESULT(S): All patients had successful placement of the Essure devices without any complications. Proximal tubal occlusion was confirmed by hysterosalpingography in 9 out of 10 patients. A 40% ongoing pregnancy rate was achieved with 20% life births after one IVF cycle and/or frozen embryo transfer. CONCLUSION(S): Proximal occlusion of hydrosalpinges with Essure devices before IVF is a successful treatment for patients with a contraindication for salpingectomy. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Authors: Kenan Omurtag; Natalia M Grindler; Kimberly A Roehl; Gordon Wright Bates; Angeline N Beltsos; Randall R Odem; Emily S Jungheim Journal: Fertil Steril Date: 2012-03-09 Impact factor: 7.329