| Literature DB >> 19145628 |
Keiichi Kawanabe1, Kentaro Ise, Koji Goto, Haruhiko Akiyama, Takashi Nakamura, Ayumi Kaneuji, Tanzo Sugimori, Tadami Matsumoto.
Abstract
A method has been developed for creating a bioactive coating on titanium by alkaline and heat treatment, and shown that it forms a thin layer of hydroxyapatite (HA) on the surface of implants when soaked in simulated body fluid. A series of 70 cementless primary total hip arthroplasties using this coating technique on a porous titanium surface was performed, and followed up the patients for a mean period of 4.8 years. There were no instances of loosening or revision, or formation of a reactive line on the porous coating. Although radiography just after operation showed a gap between the host bone and the socket in over 70% of cases, all the gaps disappeared within a year, indicating the good osteoconduction provided by the coating. Alkaline-heat treatment of titanium to provide a thin HA coating has several advantages over plasma-spraying, including no degeneration or absorption of the HA coating, simplicity of the manufacturing process, and cost effectiveness. In addition, this method allows homogeneous deposition of bone-like apatite within a porous implant. Although this was a relatively short-term study, treatment that creates a bioactive surface on titanium and titanium alloy implants has considerable promise for clinical application. (c) 2009 Wiley Periodicals, Inc.Entities:
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Year: 2009 PMID: 19145628 DOI: 10.1002/jbm.b.31309
Source DB: PubMed Journal: J Biomed Mater Res B Appl Biomater ISSN: 1552-4973 Impact factor: 3.368