| Literature DB >> 19144369 |
Nicola Decaro1, Costantina Desario, Antonio Parisi, Vito Martella, Alessio Lorusso, Angela Miccolupo, Viviana Mari, Maria Loredana Colaianni, Alessandra Cavalli, Livia Di Trani, Canio Buonavoglia.
Abstract
The sequence of the full-length gene encoding for the main capsid protein VP2 of 58 canine parvovirus (CPV) type 2c strains, along with recent CPV-2a/2b strains, was determined and analysed in comparison with reference CPV isolates. The CPV-2c strains displayed a low genetic variability and shared amino acid changes already detected in recent CPV-2a/2b isolates, with a phylogenetic clustering accounting for their geographical distribution. Analysis of the selection pressure driving CPV evolution confirmed that the VP2 gene is under purifying selection. The emergence and global spread of the new CPV variant provides an interesting model to better understand virus evolution.Entities:
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Year: 2009 PMID： 19144369 DOI： 10.1016/j.virol.2008.12.016
Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616