Literature DB >> 19143603

Recognition of deaminated bases by archaeal family-B DNA polymerases.

Bernard A Connolly1.   

Abstract

Archaeal family-B DNA polymerases interact specifically with uracil and hypoxanthine, stalling replication on encountering these deaminated bases in DNA template strands. The present review describes X-ray structural data which elucidate the mechanism of read-ahead recognition of uracil and suggests how this is coupled to cessation of polymerization. The possible role of read-ahead recognition of uracil/hypoxanthine in DNA repair is discussed, as is the observation that the feature appears to be limited to replicative polymerases of the archaeal domain.

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Year:  2009        PMID： 19143603     DOI： 10.1042/BST0370065

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  12 in total

1.  Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins in DNA replication.

Authors:  Jeong-Yun Choi; Robert L Eoff; Matthew G Pence; Jian Wang; Martha V Martin; Eun-Jin Kim; Lindsay M Folkmann; F Peter Guengerich
Journal:  J Biol Chem       Date:  2011-07-22       Impact factor: 5.157

2.  Identification of a novel bifunctional uracil DNA glycosylase from Thermococcus barophilus Ch5.

Authors:  Likui Zhang; Donghao Jiang; Qi Gan; Haoqiang Shi; Li Miao; Yong Gong; Philippe Oger
Journal:  Appl Microbiol Biotechnol       Date:  2021-07-05       Impact factor: 4.813

Review 3.  Diversity of the DNA replication system in the Archaea domain.

Authors:  Felipe Sarmiento; Feng Long; Isaac Cann; William B Whitman
Journal:  Archaea       Date:  2014-03-26       Impact factor: 3.273

Review 4.  DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides.

Authors:  Roberto Laos; J Michael Thomson; Steven A Benner
Journal:  Front Microbiol       Date:  2014-10-31       Impact factor: 5.640

5.  Engineering processive DNA polymerases with maximum benefit at minimum cost.

Authors:  Linda J Reha-Krantz; Sandra Woodgate; Myron F Goodman
Journal:  Front Microbiol       Date:  2014-08-04       Impact factor: 5.640

6.  Hinge-initiated Primer-dependent Amplification of Nucleic Acids (HIP) - A New Versatile Isothermal Amplification Method.

Authors:  Jens Fischbach; Marcus Frohme; Jörn Glökler
Journal:  Sci Rep       Date:  2017-08-09       Impact factor: 4.379

7.  The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases.

Authors:  Henry J Russell; Tomas T Richardson; Kieran Emptage; Bernard A Connolly
Journal:  Nucleic Acids Res       Date:  2009-12       Impact factor: 16.971

8.  Unwinding of primer-templates by archaeal family-B DNA polymerases in response to template-strand uracil.

Authors:  Tomas T Richardson; Xiaohua Wu; Brian J Keith; Pauline Heslop; Anita C Jones; Bernard A Connolly
Journal:  Nucleic Acids Res       Date:  2013-01-08       Impact factor: 16.971

Review 9.  DNA polymerases as useful reagents for biotechnology - the history of developmental research in the field.

Authors:  Sonoko Ishino; Yoshizumi Ishino
Journal:  Front Microbiol       Date:  2014-08-29       Impact factor: 5.640

10.  The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG.

Authors:  Miyako Shiraishi; Sonoko Ishino; Matthew Heffernan; Isaac Cann; Yoshizumi Ishino
Journal:  Sci Rep       Date:  2018-10-25       Impact factor: 4.379
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