| Literature DB >> 19143035 |
Francisco J Fañanás1, Amadeo Fernández, Deniz Cevic, Félix Rodríguez.
Abstract
A very simple strategy for the construction of 2,3-benzofused 8-oxabicyclo[3.2.1]octane derivatives is reported. This new process is based on a platinum-catalyzed tandem intramolecular hydroalkoxylation-hydroarylation reaction of aryl-substituted pentynol derivatives. This reaction has been applied in the key step of the total synthesis of bruguierol A, allowing the synthesis of this natural product in a very straightforward manner.Entities:
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Year: 2009 PMID： 19143035 DOI： 10.1021/jo8021204
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354