BACKGROUND/AIM: Peritoneal dialysis (PD) patient survival is influenced by many factors and there is no consensus on the relative importance of these predictors, independently or combined. This study was designed to evaluate how these independent factors, alone or in various combinations, may influence PD patient survival. METHODS: A peritoneal equilibration test, subjective global assessment (SGA), and comorbid diseases (CMD) were assessed. RESULTS: On multivariate analysis, age (>60 years), CMD, malnutrition, and low RRF (<or=2 ml/min) were independent predictors of mortality. Three-year patient survival was 100, 95, 75, 49, and 0%, and the risk ratio for mortality was 1.0, 6.6, 21.9, and 85.9 in patients with none, one, two, three, and four of these risk factors, respectively. CONCLUSIONS: The combination of independent predictors of mortality in PD patients leads to a markedly increasing risk for mortality. Evaluation of a single risk factor underestimates the true impact of risk factors.
BACKGROUND/AIM: Peritoneal dialysis (PD) patient survival is influenced by many factors and there is no consensus on the relative importance of these predictors, independently or combined. This study was designed to evaluate how these independent factors, alone or in various combinations, may influence PDpatient survival. METHODS: A peritoneal equilibration test, subjective global assessment (SGA), and comorbid diseases (CMD) were assessed. RESULTS: On multivariate analysis, age (>60 years), CMD, malnutrition, and low RRF (<or=2 ml/min) were independent predictors of mortality. Three-year patient survival was 100, 95, 75, 49, and 0%, and the risk ratio for mortality was 1.0, 6.6, 21.9, and 85.9 in patients with none, one, two, three, and four of these risk factors, respectively. CONCLUSIONS: The combination of independent predictors of mortality in PDpatients leads to a markedly increasing risk for mortality. Evaluation of a single risk factor underestimates the true impact of risk factors.
Authors: Ismay N van Loon; Tom R Wouters; Franciscus T J Boereboom; Michiel L Bots; Marianne C Verhaar; Marije E Hamaker Journal: Clin J Am Soc Nephrol Date: 2016-04-26 Impact factor: 8.237
Authors: Brian Forzley; Lee Er; Helen H L Chiu; Ognjenka Djurdjev; Dan Martinusen; Rachel C Carson; Gaylene Hargrove; Adeera Levin; Mohamud Karim Journal: Palliat Med Date: 2017-07-21 Impact factor: 4.762
Authors: Brian Forzley; Helen H L Chiu; Ognjenka Djurdjev; Rachel C Carson; Gaylene Hargrove; Dan Martinusen; Mohamud Karim Journal: Can J Kidney Health Dis Date: 2017-08-18