Biology of myospryn: what's known?

Myospryn (CMYA5, cardiomyopathy-associated 5) is a muscle-specific member of the TRIM superfamily, discovered a few years ago. Properties and functions of the little-studied protein remain largely enigmatic, but identified interactions have suggested that myospryn is involved in two seemingly distinct processes, protein kinase A signalling and vesicular trafficking. Recent findings have implicated myospryn in Duchenne muscular dystrophy and cardiac disease, making it an exciting new player in the field of muscle biology and pathology.