Literature DB >> 19139772

Idiopathic granulomatous mastitis.

Erkan Ozturk1, Murat Akin, Mehmet F Can, Ismail Ozerhan, Bulent Kurt, Gokhan Yagci, Turgut Tufan.   

Abstract

OBJECTIVE: To discuss the clinical and radiological features and treatment approaches in 14 patients diagnosed with idiopathic granulomatous mastitis (GM).
METHODS: We retrospectively evaluated the clinical features, radiological findings, and treatment approaches in 14 patients with idiopathic GM in the General Surgery Department, Gulhane School of Medicine, Ankara, Turkey between April 2000 and June 2006.
RESULTS: The mean age of the patients was 34.5 years (range 27-41 years). The complaints at admission were a mass in the breast in 7 (50%) patients, an abscess and a mass in 6 (42.8%), and a skin fistula in one (7.2%). Granulomatous mastitis was unilateral in all subjects (on the right in 5 patients and on the left in 9). All of the patients underwent ultrasonographic evaluation. Mammography was performed in 8 and magnetic resonance imaging in 5 patients. Seven patients (50%) were suspected to have breast carcinoma according to radiological findings. We performed large excision in 11, incisional biopsy plus abscess drainage in one, and incisional biopsy plus abscess drainage plus medical treatment (prednisolone, methotrexate) in 2 patients. Due to the development of abscess after 9 months, drainage and large excision were also performed in one patient who received medical treatment.
CONCLUSION: Idiopathic GM is a disease that generally affects young women of reproductive age and may be mistaken for breast carcinoma in clinical and radiological evaluations. The gold standard for the diagnosis is histopathologic evaluation.

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Year:  2009        PMID: 19139772

Source DB:  PubMed          Journal:  Saudi Med J        ISSN: 0379-5284            Impact factor:   1.484


  4 in total

1.  Granulomatous mastitis: is it an autoimmune disease? Diagnostic and therapeutic dilemmas.

Authors:  Leyla Ozel; Aysun Unal; Ethem Unal; Melih Kara; Erdal Erdoğdu; Osman Krand; Pembegül Güneş; Hikmet Karagül; Serdar Demiral; M Izzet Titiz
Journal:  Surg Today       Date:  2011-11-10       Impact factor: 2.549

2.  Corticosteroid treatment in the management of idiopathic granulomatous mastitis to avoid unnecessary surgery.

Authors:  Tulay Mizrakli; Mehmet Velidedeoglu; Mucahit Yemisen; Birgul Mete; Fahrettin Kilic; Halit Yilmaz; Tulin Ozturk; Resat Ozaras; Fatih Aydogan; Asiye Perek
Journal:  Surg Today       Date:  2014-07-04       Impact factor: 2.549

3.  Erythema nodosum associated with granulomatous mastitis: report of two cases.

Authors:  Cemal Bes; Mehmet Soy; Seref Vardi; Neriman Sengul; Fahri Yilmaz
Journal:  Rheumatol Int       Date:  2009-08-23       Impact factor: 2.631

4.  Idiopathic granulomatous mastitis: a mimicking disease in a pregnant woman: a case report.

Authors:  Juan A Garcia-Rodiguez; Andrew Pattullo
Journal:  BMC Res Notes       Date:  2013-03-14
  4 in total

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