Literature DB >> 19138882

Routine biopsies in pediatric circumcision: (non) sense?

Deirdre M Bochove-Overgaauw1, Wim Gelders, Ann M A De Vylder.   

Abstract

OBJECTIVE: At our institute we usually send the foreskin after circumcision for pathological examination. Does this make sense or is it merely medical overconsumption?
MATERIAL AND METHODS: A retrospective analysis was carried out of all pediatric patients who underwent a circumcision, from August 2005 to January 2008, for persisting pathological phimosis after treatment with topical steroids. Religious circumcisions were excluded.
RESULTS: Balanitis xerotica obliterans (BXO) was diagnosed in 37 out of 135 biopsies (27%). In 19 of the 37 boys with pathological evidence of BXO (51%), the physical examination matched the pathology. Meatal stenosis was found in six cases; four were also diagnosed with BXO.
CONCLUSIONS: In this study, 27% of all biopsies were positive for BXO. The results show that the diagnosis BXO must be based on biopsy, because clinical findings underestimated the incidence of BXO by almost 50%. BXO implies a higher incidence of meatal stenosis, urethral pathology and has a known association with penile carcinoma. We conclude that there is a place for routine biopsy of the foreskin after circumcision for pathological phimosis, taking into account the potential clinical consequences when BXO is diagnosed.

Entities:  

Mesh:

Year:  2009        PMID: 19138882     DOI: 10.1016/j.jpurol.2008.11.008

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  12 in total

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2.  Underestimation of genital lichen sclerosus incidence in boys with phimosis: results from a systematic review.

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4.  Canadian Urological Association guideline on the care of the normal foreskin and neonatal circumcision in Canadian infants (full version).

Authors:  Sumit Dave; Kourosh Afshar; Luis H Braga; Peter Anderson
Journal:  Can Urol Assoc J       Date:  2017-12-01       Impact factor: 1.862

5.  Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans.

Authors:  C Holbrook; T Tsang
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Review 6.  [Lichen sclerosus in the genitourinary region].

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8.  Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans.

Authors:  Tiziana Russo; Monica Currò; Anna Barbera; Daniela Caccamo; Pietro Antonuccio; Salvatore Arena; Angela Simona Montalto; Saveria Parisi; Lucia Marseglia; Eloisa Gitto; Riccardo Ientile; Pietro Impellizzeri; Carmelo Romeo
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9.  The Association Between BXO and Obesity in Boys Undergoing Circumcision.

Authors:  Molly E Fuchs; Nicholas Beecroft; Daniel G Dajusta; Daryl J McLeod
Journal:  Glob Pediatr Health       Date:  2017-11-24

10.  Balanitis xerotica obliterans: has its diagnostic accuracy improved with time?

Authors:  Khalis Boksh; Nitin Patwardhan
Journal:  JRSM Open       Date:  2017-06-05
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