OBJECTIVES: The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS: Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic resonance imaging with echo planar imaging technique. The minimum ADC (minADC) of each tumor was pre-operatively determined from several regions of interest. The minADC of ganglioglioma was compared with that of low- or high-grade astrocytomas (astrocytoma, anaplastic astrocytoma and glioblastoma). Tumor cellularity of gangliogliomas was compared with the minADC. RESULTS: The mean minADC of the gangliogliomas (1.45 +/- 0.20 x 10(-3) mm(2)/s) was significantly higher than that of the low- or high-grade astrocytomas. Tumor cellularity of ganglioglioma was inversely correlated with the minADC value. DISCUSSION: The minADC value reflects in the low tumor cellularity of gangliogliomas and may provide a method for the differential diagnosis of ganglioglioma.
OBJECTIVES: The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS: Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic resonance imaging with echo planar imaging technique. The minimum ADC (minADC) of each tumor was pre-operatively determined from several regions of interest. The minADC of ganglioglioma was compared with that of low- or high-grade astrocytomas (astrocytoma, anaplastic astrocytoma and glioblastoma). Tumor cellularity of gangliogliomas was compared with the minADC. RESULTS: The mean minADC of the gangliogliomas (1.45 +/- 0.20 x 10(-3) mm(2)/s) was significantly higher than that of the low- or high-grade astrocytomas. Tumor cellularity of ganglioglioma was inversely correlated with the minADC value. DISCUSSION: The minADC value reflects in the low tumor cellularity of gangliogliomas and may provide a method for the differential diagnosis of ganglioglioma.
Authors: K Koral; S Zhang; L Gargan; W Moore; B Garvey; M Fiesta; M Seymour; L Yang; D Scott; N Choudhury Journal: AJNR Am J Neuroradiol Date: 2013-06-20 Impact factor: 3.825
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Authors: Matej Vrabec; Sofie Van Cauter; Uwe Himmelreich; Stefaan W Van Gool; Stefan Sunaert; Steven De Vleeschouwer; Dušan Suput; Philippe Demaerel Journal: Neuroradiology Date: 2010-11-25 Impact factor: 2.804
Authors: Kant M Matsuda; Ana Lopes-Calcas; Michael L Honke; Zoe O'Brien-Moran; Richard Buist; Michael West; Melanie Martin Journal: J Med Imaging (Bellingham) Date: 2017-09-13
Authors: Oliver Eidel; Jan-Oliver Neumann; Sina Burth; Pascal J Kieslich; Christine Jungk; Felix Sahm; Philipp Kickingereder; Karl Kiening; Andreas Unterberg; Wolfgang Wick; Heinz-Peter Schlemmer; Martin Bendszus; Alexander Radbruch Journal: PLoS One Date: 2016-07-28 Impact factor: 3.240