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Literature DB >> 19137449

Peptide immobilized on gold particles enhances cell growth.

Abstract

A multivalent ligand of thrombopoietin (TPO) was prepared by immobilization of mimetic peptides on gold particles. An effective peptide ligand containing cysteine was designed to enhance the growth of TPO-sensitive cells. The peptide was then immobilized on gold particles by self assembly. The multivalent ligand enhanced the growth of TPO-dependent cells and its activity was more than that of the monovalent ligand.

Entities: Chemical Gene

Year: 2009 PMID： 19137449 PMCID： PMC2652554 DOI： 10.1007/s10616-008-9179-3

Source DB: PubMed Journal: Cytotechnology ISSN： 0920-9069 Impact factor: 2.058

15 in total

1. A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation.

Authors: R A Nash; R Kurzrock; J DiPersio; J Vose; C Linker; D Maharaj; A P Nademanee; R Negrin; S Nimer; H Shulman; M Ashby; D Jones; F R Appelbaum; R Champlin
Journal: Biol Blood Marrow Transplant Date: 2000 Impact factor: 5.742

Review 2. Multivalent interactions at interfaces.

Authors: Jurriaan Huskens
Journal: Curr Opin Chem Biol Date: 2006-09-26 Impact factor: 8.822

3. The distribution and radiation effects of intravenously administered colloidal Au198 in man.

Authors: S W ROOT; G A ANDREWS; R M KNISELEY; M P TYOR
Journal: Cancer Date: 1954-09 Impact factor: 6.860

4. Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.

Authors: S E Cwirla; P Balasubramanian; D J Duffin; C R Wagstrom; C M Gates; S C Singer; A M Davis; R L Tansik; L C Mattheakis; C M Boytos; P J Schatz; D P Baccanari; N C Wrighton; R W Barrett; W J Dower
Journal: Science Date: 1997-06-13 Impact factor: 47.728

5. Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation.

Authors: H Morita; T Tahara; A Matsumoto; T Kato; H Miyazaki; H Ohashi
Journal: FEBS Lett Date: 1996-10-21 Impact factor: 4.124

6. Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.

Authors: K J Duffy; M G Darcy; E Delorme; S B Dillon; D F Eppley; C Erickson-Miller; L Giampa; C B Hopson; Y Huang; R M Keenan; P Lamb; L Leong; N Liu; S G Miller; A T Price; J Rosen; R Shah; T N Shaw; H Smith; K C Stark; S S Tian; C Tyree; K J Wiggall; L Zhang; J I Luengo
Journal: J Med Chem Date: 2001-10-25 Impact factor: 7.446

7. In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags.

Authors: Ximei Qian; Xiang-Hong Peng; Dominic O Ansari; Qiqin Yin-Goen; Georgia Z Chen; Dong M Shin; Lily Yang; Andrew N Young; May D Wang; Shuming Nie
Journal: Nat Biotechnol Date: 2007-12-23 Impact factor: 54.908

8. Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities.

Authors: Koji Inagaki; Tomohiro Oda; Yuichi Naka; Hisashi Shinkai; Norio Komatsu; Hiroyuki Iwamura
Journal: Blood Date: 2004-03-04 Impact factor: 22.113