Literature DB >> 19137131

Drugs for the treatment of diabetes complications. Zycose: a new player in the field?

Alin Stirban1.   

Abstract

Zycose is a newly released (2006) combined medication containing folic acid (1 mg) benfotiamine (150 mg) and benzamine (850 mg), a proprietary blend of para-aminobenzoic acid (PABA), vitamin E and alpha-lipoic acid (ALA). Zycose protects vascular, retinal and kidney function by improving cellular health and promoting peripheral nerve health in people with diabetes. Zycose's therapeutic benefit is believed to be due to the additive effects of its compounds on lowering homocysteine levels (folic acid), reducing the production of advanced glycation end products (benfotiamine), improving endothelial function (folic acid, benfotiamine, ALA), reducing oxidative stress (ALA, vitamin E) and reducing carbonyl stress (benzamine). The complex composition of Zycose allows the therapeutic intervention of several hyperglycemiamediated disorders. The compound consists mainly of vitamins, therefore explaining, in part, the good safety profile and reduced adverse effects. Copyright 2008 Prous Science, S.A.U. or its licensors. All rights reserved.

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Year:  2008        PMID: 19137131     DOI: 10.1358/dot.2008.44.10.1183086

Source DB:  PubMed          Journal:  Drugs Today (Barc)        ISSN: 1699-3993            Impact factor:   2.245


  2 in total

1.  Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.

Authors:  Paras Kumar Mishra; Srikanth Givvimani; Naira Metreveli; Suresh C Tyagi
Journal:  Biochem Biophys Res Commun       Date:  2010-09-15       Impact factor: 3.575

2.  Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.

Authors:  Cimen Karasu
Journal:  Open Cardiovasc Med J       Date:  2010-11-26
  2 in total

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