Literature DB >> 19137109

Hyphenated tools for phospholipidomics.

Jan Willmann1, Dieter Leibfritz, Herbert Thiele.   

Abstract

The analysis of intact and underivatised lipids in body fluids as well as in cell and tissue extracts is of utmost importance in the field of early diagnosis. Therefore, fast, reliable, and automated analytical methods are needed to detect known as well as unknown species. The combination of solid phase extraction, high-performance liquid chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy are best at meeting this challenge. Herein, we show a workflow for the reliable analysis of individual components in phosphatidylethanolamine extracts. The limitations and advantages of the individual methods are discussed.

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Year:  2008        PMID： 19137109      PMCID： PMC2563922     

Source DB:  PubMed          Journal:  J Biomol Tech        ISSN： 1524-0215


  29 in total

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Authors:  Alan P Watt; Russell J Mortishire-Smith; Ute Gerhard; Steven R Thomas
Journal:  Curr Opin Drug Discov Devel       Date:  2003-01

Review 2.  Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples.

Authors:  Xianlin Han; Richard W Gross
Journal:  Mass Spectrom Rev       Date:  2005 May-Jun       Impact factor: 10.946

Review 3.  An introduction to the potential of 1H-, 31P- and 13C-NMR-spectroscopy.

Authors:  D Leibfritz
Journal:  Anticancer Res       Date:  1996 May-Jun       Impact factor: 2.480

4.  Lipids isolated from bone induce the migration of human breast cancer cells.

Authors:  Jeane Silva; Somsankar Dasgupta; Guanghu Wang; Kannan Krishnamurthy; Edmond Ritter; Erhard Bieberich
Journal:  J Lipid Res       Date:  2006-01-26       Impact factor: 5.922

Review 5.  Mass spectrometry-based "omics" technologies in cancer diagnostics.

Authors:  Xuewu Zhang; Dong Wei; Yeeleng Yap; Lin Li; Siyuan Guo; Feng Chen
Journal:  Mass Spectrom Rev       Date:  2007 May-Jun       Impact factor: 10.946

6.  Improved high-performance liquid chromatographic method for the separation and quantification of lipid classes: application to fish lipids.

Authors:  C Silversand; C Haux
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1997-12-05

7.  Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry.

Authors:  B Brügger; G Erben; R Sandhoff; F T Wieland; W D Lehmann
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-18       Impact factor: 11.205

Review 8.  Application of high resolution 31P NMR spectroscopy to the characterization of the phospholipid composition of tissues and body fluids - a methodological review.

Authors:  Jürgen Schiller; Klaus Arnold
Journal:  Med Sci Monit       Date:  2002-11

9.  Quantitative release of fatty acids from lipids by a simple hydrolysis procedure.

Authors:  M I Aveldaño; L A Horrocks
Journal:  J Lipid Res       Date:  1983-08       Impact factor: 5.922

10.  Differentiation of primary or metastatic lung carcinoma by phospholipid analysis. A new approach for lung carcinoma differentiation.

Authors:  K Itoh; H Natori; A Suzuki; T Akino
Journal:  Cancer       Date:  1986-04-01       Impact factor: 6.860
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  1 in total

Review 1.  The foundations and development of lipidomics.

Authors:  Xianlin Han; Richard W Gross
Journal:  J Lipid Res       Date:  2021-12-22       Impact factor: 5.922
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