Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 GDNF--a potential target to treat addiction.

Literature DB >> 19136027

GDNF--a potential target to treat addiction.

Abstract

The glial cell line-derived neurotrophic factor (GDNF) is a secreted protein, best known for its role in the development of the central and peripheral nervous systems and the survival of adult dopaminergic neurons. More recently, accumulating evidence suggests that GDNF plays a unique role in negatively regulating the actions of drugs of abuse. In this article, we review these data and highlight the possibility that the GDNF pathway may be a promising target for the treatment of addiction.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2008 PMID： 19136027 PMCID： PMC3682485 DOI： 10.1016/j.pharmthera.2008.12.001

Source DB: PubMed Journal: Pharmacol Ther ISSN： 0163-7258 Impact factor: 12.310

150 in total

1. Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts.

Authors: G Paratcha; F Ledda; L Baars; M Coulpier; V Besset; J Anders; R Scott; C F Ibáñez
Journal: Neuron Date: 2001-01 Impact factor: 17.173

2. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

Authors: J H Kordower; M E Emborg; J Bloch; S Y Ma; Y Chu; L Leventhal; J McBride; E Y Chen; S Palfi; B Z Roitberg; W D Brown; J E Holden; R Pyzalski; M D Taylor; P Carvey; Z Ling; D Trono; P Hantraye; N Déglon; P Aebischer
Journal: Science Date: 2000-10-27 Impact factor: 47.728

3. In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats.

Authors: M H Baumann; R B Rothman; J P Pablo; D C Mash
Journal: J Pharmacol Exp Ther Date: 2001-05 Impact factor: 4.030

Review 4. Drug insight: Cabergoline and bromocriptine in the treatment of hyperprolactinemia in men and women.

Authors: Annamaria Colao; Antonella Di Sarno; Ermelinda Guerra; Monica De Leo; Alberto Mentone; Gaetano Lombardi
Journal: Nat Clin Pract Endocrinol Metab Date: 2006-04

5. RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice.

Authors: Sanjay Jain; Judith P Golden; David Wozniak; Elizabeth Pehek; Eugene M Johnson; Jeffrey Milbrandt
Journal: J Neurosci Date: 2006-10-25 Impact factor: 6.167

6. Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation.

Authors: R Gerlai; A McNamara; D L Choi-Lundberg; M Armanini; J Ross; L Powell-Braxton; H S Phillips
Journal: Eur J Neurosci Date: 2001-10 Impact factor: 3.386

Review 7. Trk receptors: mediators of neurotrophin action.

Authors: A Patapoutian; L F Reichardt
Journal: Curr Opin Neurobiol Date: 2001-06 Impact factor: 6.627

8. c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

Authors: M Encinas; M G Tansey; B A Tsui-Pierchala; J X Comella; J Milbrandt; E M Johnson
Journal: J Neurosci Date: 2001-03-01 Impact factor: 6.167

Review 9. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory.

Authors: J D Sweatt
Journal: J Neurochem Date: 2001-01 Impact factor: 5.372

10. Ca(2+) binding protein frequenin mediates GDNF-induced potentiation of Ca(2+) channels and transmitter release.

Authors: C Y Wang; F Yang; X He; A Chow; J Du; J T Russell; B Lu
Journal: Neuron Date: 2001-10-11 Impact factor: 17.173

35 in total

1. Increasing the specificity of neurotrophic factors.

Authors: Moses V Chao
Journal: Proc Natl Acad Sci U S A Date: 2010-07-23 Impact factor: 11.205

2. Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system.

Authors: Jun Wang; Sebastien Carnicella; Somayeh Ahmadiantehrani; Dao-Yao He; Segev Barak; Viktor Kharazia; Sami Ben Hamida; Agustin Zapata; Toni S Shippenberg; Dorit Ron
Journal: J Neurosci Date: 2010-10-27 Impact factor: 6.167

3. Ethanol and nicotine interaction within the posterior ventral tegmental area in male and female alcohol-preferring rats: evidence of synergy and differential gene activation in the nucleus accumbens shell.

Authors: William A Truitt; Sheketha R Hauser; Gerald A Deehan; Jamie E Toalston; Jessica A Wilden; Richard L Bell; William J McBride; Zachary A Rodd
Journal: Psychopharmacology (Berl) Date: 2014-08-26 Impact factor: 4.530

4. Endogenous GDNF in ventral tegmental area and nucleus accumbens does not play a role in the incubation of heroin craving.

Authors: Mikko Airavaara; Charles L Pickens; Anna L Stern; Kristina A Wihbey; Brandon K Harvey; Jennifer M Bossert; Qing-Rong Liu; Barry J Hoffer; Yavin Shaham
Journal: Addict Biol Date: 2010-12-23 Impact factor: 4.280

5. Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration.

Authors: Sebastien Carnicella; Dao-Yao He; Quinn V Yowell; Stanley D Glick; Dorit Ron
Journal: Addict Biol Date: 2010-10 Impact factor: 4.280

6. Alcohol reward, dopamine depletion, and GDNF.

Authors: Charles L Pickens; Donna J Calu
Journal: J Neurosci Date: 2011-10-19 Impact factor: 6.167

7. Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking.

Authors: Segev Barak; Sebastien Carnicella; Quinn V Yowell; Dorit Ron
Journal: J Neurosci Date: 2011-07-06 Impact factor: 6.167