Literature DB >> 19133782

X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.

Kalyaneswar Mandal1, Brad L Pentelute, Valentina Tereshko, Anthony A Kossiakoff, Stephen B H Kent.   

Abstract

Racemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19133782      PMCID： PMC2647749          DOI： 10.1021/ja8077973

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  17 in total

Review 1.  Advances in direct methods for protein crystallography.

Authors:  I Usón; G M Sheldrick
Journal:  Curr Opin Struct Biol       Date:  1999-10       Impact factor: 6.809

2.  Ab initio structure determination of a small protein, rubredoxin, by direct methods.

Authors:  M Mukherjee
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1999-04

3.  Refinement of macromolecular structures by the maximum-likelihood method.

Authors:  G N Murshudov; A A Vagin; E J Dodson
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1997-05-01

4.  The Direct Methods of X-ray Crystallography.

Authors:  H Hauptman
Journal:  Science       Date:  1986-07-11       Impact factor: 47.728

5.  Centrosymmetric crystals of biomolecules: the racemate method.

Authors:  J M Berg; N W Goffeney
Journal:  Methods Enzymol       Date:  1997       Impact factor: 1.600

6.  The structure of a centrosymmetric protein crystal.

Authors:  L E Zawadzke; J M Berg
Journal:  Proteins       Date:  1993-07

7.  Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1.

Authors:  W R Patterson; D H Anderson; W F DeGrado; D Cascio; D Eisenberg
Journal:  Protein Sci       Date:  1999-07       Impact factor: 6.725

8.  Structural differences in D and L-monellin in the crystals of racemic mixture.

Authors:  L W Hung; M Kohmura; Y Ariyoshi; S H Kim
Journal:  J Mol Biol       Date:  1999-01-08       Impact factor: 5.469

9.  Structure determination of racemic trichogin A IV using centrosymmetric crystals.

Authors:  C Toniolo; C Peggion; M Crisma; F Formaggio; X Shui; D S Eggleston
Journal:  Nat Struct Biol       Date:  1994-12

10.  Solution structure of BmBKTx1, a new BKCa1 channel blocker from the Chinese scorpion Buthus martensi Karsch.

Authors:  Zheng Cai; Chenqi Xu; Yingqi Xu; Wuyuan Lu; Cheng-wu Chi; Yunyu Shi; Jihui Wu
Journal:  Biochemistry       Date:  2004-04-06       Impact factor: 3.162
View more
  11 in total

1.  New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization.

Authors:  Pawel Sledz; Heping Zheng; Krzysztof Murzyn; Maksymilian Chruszcz; Matthew D Zimmerman; Mahendra D Chordia; Andrzej Joachimiak; Wladek Minor
Journal:  Protein Sci       Date:  2010-07       Impact factor: 6.725

2.  High-resolution structures of a heterochiral coiled coil.

Authors:  David E Mortenson; Jay D Steinkruger; Dale F Kreitler; Dominic V Perroni; Gregory P Sorenson; Lijun Huang; Ritesh Mittal; Hyun Gi Yun; Benjamin R Travis; Mahesh K Mahanthappa; Katrina T Forest; Samuel H Gellman
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-12       Impact factor: 11.205

3.  Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.

Authors:  David E Mortenson; Kenneth A Satyshur; Ilia A Guzei; Katrina T Forest; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2012-01-18       Impact factor: 15.419

4.  Racemic crystallography--easy crystals and easy structures: what's not to like?

Authors:  Brian W Matthews
Journal:  Protein Sci       Date:  2009-06       Impact factor: 6.725

5.  Fully convergent chemical synthesis of ester insulin: determination of the high resolution X-ray structure by racemic protein crystallography.

Authors:  Michal Avital-Shmilovici; Kalyaneswar Mandal; Zachary P Gates; Nelson B Phillips; Michael A Weiss; Stephen B H Kent
Journal:  J Am Chem Soc       Date:  2013-02-08       Impact factor: 15.419

6.  Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio.

Authors:  Dorothee Liebschner; Krzysztof Brzezinski; Miroslawa Dauter; Zbigniew Dauter; Marta Nowak; Józef Kur; Marcin Olszewski
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2012-11-09

7.  Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue.

Authors:  Zvi Hayouka; David E Mortenson; Dale F Kreitler; Bernard Weisblum; Katrina T Forest; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2013-10-08       Impact factor: 15.419

8.  Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography.

Authors:  Bobo Dang; Tomoya Kubota; Kalyaneswar Mandal; Francisco Bezanilla; Stephen B H Kent
Journal:  J Am Chem Soc       Date:  2013-08-06       Impact factor: 15.419

9.  Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.

Authors:  Kalyaneswar Mandal; Brad L Pentelute; Valentina Tereshko; Vilasak Thammavongsa; Olaf Schneewind; Anthony A Kossiakoff; Stephen B H Kent
Journal:  Protein Sci       Date:  2009-06       Impact factor: 6.725

Review 10.  Mirror image proteins.

Authors:  Le Zhao; Wuyuan Lu
Journal:  Curr Opin Chem Biol       Date:  2014-10-01       Impact factor: 8.822
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.