Literature DB >> 19132387

Ulceroglandular tularemia in a toddler in Germany after a mosquito bite.

Christof A Hanke1, Joerg-Elard Otten, Reinhard Berner, Annerose Serr, Wolf Splettstoesser, Christian von Schnakenburg.   

Abstract

INTRODUCTION: Although tularemia is a long-known disease, its significance had diminished over the last decades in Middle Europe. However, over the past years, there is new evidence suggesting that tularemia has re-emerged in Germany. In 2007, the highest number of human cases for almost 50 years has been notified. Beside typical vectors, new ways of transmission seem to gain significance. So far, mosquito bite-transmitted tularemia has only been known from Scandinavia but not from Middle Europe. CASE REPORT: We report the first case of a 1-year-old toddler from Southwestern Germany with mosquito bite-associated ulceroglandular tularaemia. The new and interesting features of this case are the young age of the patient and the unusual transmission route. The available data suggesting changes in the epidemiology for tularemia in Germany are reviewed. This is an interesting case of infantile tularemia with a very unusual transmission route, highlighting ongoing changes in the epidemiology of tularemia in Germany.

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Year:  2009        PMID: 19132387     DOI: 10.1007/s00431-008-0862-3

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  14 in total

1.  [Epidemiology of tularemia in the region of Mecklenburg].

Authors:  H MOCHMANN
Journal:  Munch Med Wochenschr       Date:  1957-08-09

2.  Tularemia in Denmark: identification of a Francisella tularensis subsp. holarctica strain by real-time PCR and high-resolution typing by multiple-locus variable-number tandem repeat analysis.

Authors:  Mona Byström; Sidsel Böcher; Anna Magnusson; Jørgen Prag; Anders Johansson
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

Review 3.  Diagnostic procedures in tularaemia with special focus on molecular and immunological techniques.

Authors:  W D Splettstoesser; H Tomaso; S Al Dahouk; H Neubauer; P Schuff-Werner
Journal:  J Vet Med B Infect Dis Vet Public Health       Date:  2005-08

Review 4.  Tularemia in children caused by Francisella tularensis biovar palaearctica.

Authors:  M Uhari; H Syrjälä; A Salminen
Journal:  Pediatr Infect Dis J       Date:  1990-02       Impact factor: 2.129

5.  A novel screening ELISA and a confirmatory Western blot useful for diagnosis and epidemiological studies of tularemia.

Authors:  P Schmitt; W Splettstösser; M Porsch-Ozcürümez; E J Finke; R Grunow
Journal:  Epidemiol Infect       Date:  2005-08       Impact factor: 2.451

6.  Ciprofloxacin for treatment of tularemia in children.

Authors:  A Johansson; L Berglund; L Gothefors; A Sjöstedt; A Tärnvik
Journal:  Pediatr Infect Dis J       Date:  2000-05       Impact factor: 2.129

7.  Re-emergence of Francisella tularensis in Germany: fatal tularaemia in a colony of semi-free-living marmosets (Callithrix jacchus).

Authors:  W D Splettstoesser; K Mätz-Rensing; E Seibold; H Tomaso; S Al Dahouk; R Grunow; S Essbauer; A Buckendahl; E-J Finke; H Neubauer
Journal:  Epidemiol Infect       Date:  2007-02-19       Impact factor: 2.451

8.  Detection of Francisella tularensis in ulcers of patients with tularemia by PCR.

Authors:  A Sjöstedt; U Eriksson; L Berglund; A Tärnvik
Journal:  J Clin Microbiol       Date:  1997-05       Impact factor: 5.948

9.  Molecular characterization of nocardioform actinomycetes in activated sludge by 16S rRNA analysis.

Authors:  M Schuppler; F Mertens; G Schön; U B Göbel
Journal:  Microbiology       Date:  1995-02       Impact factor: 2.777

10.  Development of a real-time PCR assay for detection and quantification of Francisella tularensis.

Authors:  Osamu Fujita; Masashi Tatsumi; Kiyoshi Tanabayashi; Akio Yamada
Journal:  Jpn J Infect Dis       Date:  2006-02       Impact factor: 1.362

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  9 in total

1.  Reciprocal analysis of Francisella novicida infections of a Drosophila melanogaster model reveal host-pathogen conflicts mediated by reactive oxygen and imd-regulated innate immune response.

Authors:  Madeleine G Moule; Denise M Monack; David S Schneider
Journal:  PLoS Pathog       Date:  2010-08-26       Impact factor: 6.823

2.  Detection of Francisella tularensis in Alaskan mosquitoes (Diptera: Culicidae) and assessment of a laboratory model for transmission.

Authors:  Alison N Triebenbach; Sigrid J Vogl; Leda Lotspeich-Cole; Derek S Sikes; George M Happ; Karsten Hueffer
Journal:  J Med Entomol       Date:  2010-07       Impact factor: 2.278

3.  Transstadial transmission of Francisella tularensis holarctica in mosquitoes, Sweden.

Authors:  Jan O Lundström; Ann-Christin Andersson; Stina Bäckman; Martina L Schäfer; Mats Forsman; Johanna Thelaus
Journal:  Emerg Infect Dis       Date:  2011-05       Impact factor: 6.883

Review 4.  Human tularemia in Italy. Is it a re-emerging disease?

Authors:  D D'Alessandro; C Napoli; A Nusca; A Bella; E Funari
Journal:  Epidemiol Infect       Date:  2014-10-22       Impact factor: 4.434

5.  The potential for flower nectar to allow mosquito to mosquito transmission of Francisella tularensis.

Authors:  Adam Kenney; Austin Cusick; Jessica Payne; Anna Gaughenbaugh; Andrea Renshaw; Jenna Wright; Roger Seeber; Rebecca Barnes; Aleksandr Florjanczyk; Joseph Horzempa
Journal:  PLoS One       Date:  2017-05-09       Impact factor: 3.240

Review 6.  Tularemia in Germany-A Re-emerging Zoonosis.

Authors:  Mirko Faber; Klaus Heuner; Daniela Jacob; Roland Grunow
Journal:  Front Cell Infect Microbiol       Date:  2018-02-16       Impact factor: 5.293

7.  Genotyping of Francisella tularensis subsp. holarctica from Hares in Germany.

Authors:  Jörg Linde; Timo Homeier-Bachmann; Alexandra Dangel; Julia M Riehm; David Sundell; Caroline Öhrman; Mats Forsman; Herbert Tomaso
Journal:  Microorganisms       Date:  2020-12-05

8.  Pediatric Tularemia-A Case Series From a Single Center in Switzerland.

Authors:  Nina Schöbi; Philipp K A Agyeman; Andrea Duppenthaler; Andreas Bartenstein; Peter M Keller; Franziska Suter-Riniker; Kristina M Schmidt; Matthias V Kopp; Christoph Aebi
Journal:  Open Forum Infect Dis       Date:  2022-06-11       Impact factor: 4.423

Review 9.  Vector-Borne Tularemia: A Re-Emerging Cause of Cervical Lymphadenopathy.

Authors:  Kaja Troha; Nina Božanić Urbančič; Miša Korva; Tatjana Avšič-Županc; Saba Battelino; Domen Vozel
Journal:  Trop Med Infect Dis       Date:  2022-08-16
  9 in total

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