Literature DB >> 19129626

Purification and characterization of the first archaeal glutamate decarboxylase from Pyrococcus horikoshii.

Han-Woo Kim1, Yasuhiro Kashima, Kazuhiko Ishikawa, Naoko Yamano.   

Abstract

Glutamate decarboxylase (GAD) from the archaeon Pyrococcus horikoshii was successfully expressed and purified, with the aim of developing a hyperthermostable GAD for industrial applications. Its biochemical properties were different from those reported for other GADs. The enzyme had broad substrate specificity, and its optimum pH and temperature were pH 8.0 and > 97 degrees C.

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Year:  2009        PMID: 19129626     DOI: 10.1271/bbb.80583

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  7 in total

1.  An archaeal glutamate decarboxylase homolog functions as an aspartate decarboxylase and is involved in β-alanine and coenzyme A biosynthesis.

Authors:  Hiroya Tomita; Yuusuke Yokooji; Takuya Ishibashi; Tadayuki Imanaka; Haruyuki Atomi
Journal:  J Bacteriol       Date:  2014-01-10       Impact factor: 3.490

Review 2.  Biotechnological advances and perspectives of gamma-aminobutyric acid production.

Authors:  Ning Xu; Liang Wei; Jun Liu
Journal:  World J Microbiol Biotechnol       Date:  2017-02-28       Impact factor: 3.312

3.  β-alanine biosynthesis in Methanocaldococcus jannaschii.

Authors:  Yu Wang; Huimin Xu; Robert H White
Journal:  J Bacteriol       Date:  2014-06-02       Impact factor: 3.490

4.  Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice.

Authors:  Gil Sharon; Nikki Jamie Cruz; Dae-Wook Kang; Michael J Gandal; Bo Wang; Young-Mo Kim; Erika M Zink; Cameron P Casey; Bryn C Taylor; Christianne J Lane; Lisa M Bramer; Nancy G Isern; David W Hoyt; Cecilia Noecker; Michael J Sweredoski; Annie Moradian; Elhanan Borenstein; Janet K Jansson; Rob Knight; Thomas O Metz; Carlos Lois; Daniel H Geschwind; Rosa Krajmalnik-Brown; Sarkis K Mazmanian
Journal:  Cell       Date:  2019-05-30       Impact factor: 66.850

5.  Modular Enzymatic Cascade Synthesis of Vitamin B5 and Its Derivatives.

Authors:  Mohammad Z Abidin; Thangavelu Saravanan; Jielin Zhang; Pieter G Tepper; Erick Strauss; Gerrit J Poelarends
Journal:  Chemistry       Date:  2018-10-30       Impact factor: 5.236

6.  Identification of new glutamate decarboxylases from Streptomyces for efficient production of γ-aminobutyric acid in engineered Escherichia coli.

Authors:  Haina Yuan; Hongbo Wang; Ozkan Fidan; Yong Qin; Gongnian Xiao; Jixun Zhan
Journal:  J Biol Eng       Date:  2019-03-21       Impact factor: 4.355

7.  Characterization of three glutamate decarboxylases from Bacillus spp. for efficient γ-aminobutyric acid production.

Authors:  Lei Sun; Yingguo Bai; Xiu Zhang; Cheng Zhou; Jie Zhang; Xiaoyun Su; Huiying Luo; Bin Yao; Yuan Wang; Tao Tu
Journal:  Microb Cell Fact       Date:  2021-08-04       Impact factor: 5.328

  7 in total

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