Literature DB >> 191290

Effects of TSH and cyclic AMP on the human thyroid cells cultured in a chemically defined medium.

Y Kaneko.   

Abstract

In a serum-free, chemically defined medium human thyroid cells elongated remarkably and resembled fibroblastic cells. They retained the cyclic AMP response to TSH and the supplement of medium with TSH or dibutyryl cyclic AMP permitted the preservation of epithelial nature by the cells. Cyclic AMP of the cells of epithelial nature was higher than those of fibroblastic appearance.

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Year:  1977        PMID： 191290     DOI： 10.1007/bf02124113

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Restoration of sensitivity of cultured hepatoma cells to cyclic nucleotides shows permissive effect of dexamethasone.

Authors:  D K Granner
Journal:  Nature       Date:  1976-02-19       Impact factor: 49.962

2.  IN VITRO EFFECTS OF THYROTROPIC HORMONE. I. ON THE PATTERN OF ORGANIZATION OF MONOLAYER CULTURES OF ISOLATED SHEEP THYROID GLAND CELLS.

Authors:  P R KERKOF; P J LONG; I L CHAIKOFF
Journal:  Endocrinology       Date:  1964-02       Impact factor: 4.736

3.  Growth control and cyclic alterations of cyclic AMP in the cell cycle.

Authors:  M M Burger; B M Bombik; B M Breckenridge; J R Sheppard
Journal:  Nat New Biol       Date:  1972-10-11

4.  Thyrotrophin-induced aggregation and reorganization into follicles of isolated porcine-thyroid cells. 1. Mechanism of action of thyrotrophin and metabolic properties.

Authors:  S Lissitzky; G Fayet; A Giraud; B Verrier; J Torresani
Journal:  Eur J Biochem       Date:  1971-12-22

5.  Further changes in differentiation state accompanying the conversion of Chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones.

Authors:  A W Hsie; C Jones; T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1971-07       Impact factor: 11.205

6.  Stimulation by insulin of cell elongation and microtubule assembly in embryonic chick-lens epithelia.

Authors:  J Piatigorsky; S S Rothschild; M Wollberg
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

7.  Influence of seeding density on multicellular organization and nuclear events in cultures of normal and neoplastic mouse mammary epithelium.

Authors:  N K Das; H L Hosick; S Nandi
Journal:  J Natl Cancer Inst       Date:  1974-03       Impact factor: 13.506

8.  Replacement of serum by hormones permits growth of cells in a defined medium.

Authors:  I Hayashi; G H Sato
Journal:  Nature       Date:  1976-01-15       Impact factor: 49.962

9.  Cyclic AMP level of human thyroid cells in monolayer culture. TSH induced refractoriness to TSH action.

Authors:  Y Kaneko
Journal:  Horm Metab Res       Date:  1976-05       Impact factor: 2.936
  9 in total

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