OBJECTIVES:Nasal irrigation is a popular adjunctive therapy after sinonasal surgery. The objective of this study was to determine the efficacy of nasal irrigation after functional endoscopic sinus surgery (FESS). METHODS:Patients with chronic rhinosinusitis (CRS) who underwent FESS were enrolled. The preoperative computed tomography (CT) Lund-Mackay staging, Lund symptom, and endoscopy scores were assessed. All patients received postoperative endoscopic débridement and medical treatment and were randomly allocated to receive nasal irrigation for 3 months or not. The symptom and endoscopy scores were repeatedly measured at 2 weeks and 1, 2, and 3 months postoperatively. RESULTS:Seventy-seven subjects completed the study. When patients were classified as having either severe or mild CRS (CT score > 12 or < or = 12, respectively), the patients with mild CRS in the irrigation group had a significantly better endoscopy score and symptom score change rates than those in the nonirrigation group (p = .019 and .032, respectively), but there were no significant differences in those outcomes between irrigation and nonirrigation groups in patients with severe CRS. CONCLUSIONS: Our results showed that nasal irrigation is an effective post-FESS management in patients with mild CRS. However, the efficacy of nasal irrigation in patients with severe CRS needs further investigation.
RCT Entities:
OBJECTIVES: Nasal irrigation is a popular adjunctive therapy after sinonasal surgery. The objective of this study was to determine the efficacy of nasal irrigation after functional endoscopic sinus surgery (FESS). METHODS:Patients with chronic rhinosinusitis (CRS) who underwent FESS were enrolled. The preoperative computed tomography (CT) Lund-Mackay staging, Lund symptom, and endoscopy scores were assessed. All patients received postoperative endoscopic débridement and medical treatment and were randomly allocated to receive nasal irrigation for 3 months or not. The symptom and endoscopy scores were repeatedly measured at 2 weeks and 1, 2, and 3 months postoperatively. RESULTS: Seventy-seven subjects completed the study. When patients were classified as having either severe or mild CRS (CT score > 12 or < or = 12, respectively), the patients with mild CRS in the irrigation group had a significantly better endoscopy score and symptom score change rates than those in the nonirrigation group (p = .019 and .032, respectively), but there were no significant differences in those outcomes between irrigation and nonirrigation groups in patients with severe CRS. CONCLUSIONS: Our results showed that nasal irrigation is an effective post-FESS management in patients with mild CRS. However, the efficacy of nasal irrigation in patients with severe CRS needs further investigation.
Authors: Kai Zhao; John R Craig; Noam A Cohen; Nithin D Adappa; Sammy Khalili; James N Palmer Journal: Laryngoscope Date: 2015-10-15 Impact factor: 3.325
Authors: Cindy M Liu; Michael A Kohanski; Michelle Mendiola; Katerina Soldanova; Michael G Dwan; Richard Lester; Lora Nordstrom; Lance B Price; Andrew P Lane Journal: Int Forum Allergy Rhinol Date: 2014-12-29 Impact factor: 3.858