OBJECTIVE: Metastasis of renal cell carcinoma (RCC) to the head and neck is a relatively uncommon phenomenon, but such lesions can be the initial presentation of disease. RCC should be considered a source for lesions in this region, especially in patients who have received a previous diagnosis of RCC. METHODS: In this study, we review the presentation, management, and outcomes for 21 patients with documented metastasis of RCC to the head and neck outside the central nervous system. This study is a retrospective review of cases ascertained during a 17-year period from a large teaching hospital. RESULTS: Of the 21 patients observed, 10 were found to have metastatic disease at the time of RCC diagnosis, involving the head and neck in 5 cases. The most common sites of head and neck metastasis were to bone (n = 6), skin and subcutaneous tissue (n = 6), and lymph nodes (n = 5). CONCLUSIONS: This study is a reminder to consider a renal primary tumour for metastatic disease identified in the head and neck, particularly metastases with a "clear cell" histologic pattern. A head and neck metastasis may occasionally be the presenting sign in a patient with RCC, or it may follow the primary diagnosis by many years.
OBJECTIVE:Metastasis of renal cell carcinoma (RCC) to the head and neck is a relatively uncommon phenomenon, but such lesions can be the initial presentation of disease. RCC should be considered a source for lesions in this region, especially in patients who have received a previous diagnosis of RCC. METHODS: In this study, we review the presentation, management, and outcomes for 21 patients with documented metastasis of RCC to the head and neck outside the central nervous system. This study is a retrospective review of cases ascertained during a 17-year period from a large teaching hospital. RESULTS: Of the 21 patients observed, 10 were found to have metastatic disease at the time of RCC diagnosis, involving the head and neck in 5 cases. The most common sites of head and neck metastasis were to bone (n = 6), skin and subcutaneous tissue (n = 6), and lymph nodes (n = 5). CONCLUSIONS: This study is a reminder to consider a renal primary tumour for metastatic disease identified in the head and neck, particularly metastases with a "clear cell" histologic pattern. A head and neck metastasis may occasionally be the presenting sign in a patient with RCC, or it may follow the primary diagnosis by many years.
Authors: Fernando López; Juan P Rodrigo; Carl E Silver; Missak Haigentz; Justin A Bishop; Primož Strojan; Dana M Hartl; Patrick J Bradley; William M Mendenhall; Carlos Suárez; Robert P Takes; Marc Hamoir; K Thomas Robbins; Ashok R Shaha; Jochen A Werner; Alessandra Rinaldo; Alfio Ferlito Journal: Head Neck Date: 2015-12-29 Impact factor: 3.147
Authors: Liborio Torregrossa; Maria Isabella Rotondo; Andrea Cacciato Insilla; David Galleri; Federica Guidoccio; Paolo Miccoli; Virginia A Livolsi; Fulvio Basolo Journal: Oncol Lett Date: 2016-08-31 Impact factor: 2.967
Authors: Juho Suojanen; Esa Färkkilä; Tessa Helkamaa; Venla Loimu; Jyrki Törnwall; Christian Lindqvist; Jaana Hagström; Karri Mesimäki Journal: Oncol Lett Date: 2014-09-05 Impact factor: 2.967