| Literature DB >> 19128149 |
Paul Bichler1, Wesley A Chalifoux, Sara Eisler, Annabelle L K Shi Shun, Erin T Chernick, Rik R Tykwinski.
Abstract
The mechanism of the Fritsch-Buttenberg-Wiechell rearrangement of (13)C labeled precursors has been examined to determine the propensity of the alkynyl (R-CC-) group to migrate in an alkylidene carbenoid species. Reaction of dibromoolefins with n-BuLi and ketones with Me(3)SiC(Li)N(2) both demonstrate that the alkynyl moiety readily undergoes 1,2-migration from carbenoid intermediates.Entities:
Year: 2009 PMID： 19128149 DOI： 10.1021/ol8023665
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005