Literature DB >> 191279

Effects of penfluridol of dopamine-sensitive adenylate cyclase in corpus striatum and substantia nigra of rats.

U Seeber, K Kuschinsky.   

Abstract

Penfluridol, a neuroleptic with diphenylbutyl piperidine structure, blocked the dopamine-sensitive adenylate cyclase in homogenates of corpus striatum and substantia nigra of rats, probably by a competitive antagonism versus dopamine.

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Year:  1976        PMID： 191279     DOI： 10.1007/bf01924451

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  [Pharmacodynamic properties of 3-chloro-10-(3-dimethylaminopropyl)-phenothiazine hydrochloride (R.P. 4560); experimental study of a new substance used in potentialized anesthesia and in artificial hibernation].

Authors:  S COURVOISIER; J FOURNEL; R DUCROT; M KOLSKY; P KOETSCHET
Journal:  Arch Int Pharmacodyn Ther       Date:  1953-01

2.  Release of dopamine from dendrites in rat substantia nigra.

Authors:  L B Geffen; T M Jessell; A C Cuello; L L Iversen
Journal:  Nature       Date:  1976-03-18       Impact factor: 49.962

3.  Dopamine release in substantia nigra?

Authors:  J Korf; M Zieleman; B H Westerink
Journal:  Nature       Date:  1976-03-18       Impact factor: 49.962

4.  Subcellular localization of dopamine-sensitive adenylate cyclase in rat brain striatum.

Authors:  P Laduron; M Verwimp; P F Janssen; J Leysen
Journal:  Life Sci       Date:  1976-02-15       Impact factor: 5.037

5.  Drugs, neurotransmitters, and schizophrenia.

Authors:  S H Snyder; S P Banerjee; H I Yamamura; D Greenberg
Journal:  Science       Date:  1974-06-21       Impact factor: 47.728

6.  Substantia nigra of the rat contains a dopamine sensitive adenylate cyclase.

Authors:  O T Phillipson; A S Horn
Journal:  Nature       Date:  1976-06-03       Impact factor: 49.962

Review 7.  Self-inhibition by dopaminergic neurons.

Authors:  P M Groves; C J Wilson; S J Young; G V Rebec
Journal:  Science       Date:  1975-11-07       Impact factor: 47.728

8.  The effect of penfluridol and some psychotropic drugs on monoamine metabolism in central nervous system.

Authors:  T Nose; H Takemoto
Journal:  Eur J Pharmacol       Date:  1975-04       Impact factor: 4.432

9.  Dopamine-sensitive adenylate cyclase in homogenates of rat striata during ethanol and barbiturate withdrawal.

Authors:  U Seeber; K Kuschinsky
Journal:  Arch Toxicol       Date:  1976-08-18       Impact factor: 5.153

10.  Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.

Authors:  Y C Clement-Cormier; J W Kebabian; G L Petzold; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205
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