Literature DB >> 19127045

Hypersexuality following subthalamic nucleus stimulation for Parkinson's disease.

Paresh Doshi1, Pranshu Bhargava.   

Abstract

Subthalamic nucleus (STN) stimulation is an established surgical treatment for Parkinson's disease (PD). Though the motor benefits of STN stimulation are well understood, its cognitive and behavioral effects are still not fully understood. Manic psychosis, hypersexuality, pathological gambling and mood swings are associated with advanced PD. There have been reports to suggest improvement or worsening in these symptoms following STN deep brain stimulation (DBS). We report two cases as the sole behavioral side-effects of STN stimulation despite good clinical improvement on long-term follow-up. These patients and literature review suggests the complex role of STN stimulation in motor and behavioral control.

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Year:  2008        PMID: 19127045     DOI: 10.4103/0028-3886.44830

Source DB:  PubMed          Journal:  Neurol India        ISSN: 0028-3886            Impact factor:   2.117


  12 in total

1.  Weight changes in subthalamic nucleus vs globus pallidus internus deep brain stimulation: results from the COMPARE Parkinson disease deep brain stimulation cohort.

Authors:  Maren C Locke; Samuel S Wu; Kelly D Foote; Marco Sassi; Charles E Jacobson; Ramon L Rodriguez; Hubert H Fernandez; Michael S Okun
Journal:  Neurosurgery       Date:  2011-05       Impact factor: 4.654

2.  Wireless Instantaneous Neurotransmitter Concentration System: electrochemical monitoring of serotonin using fast-scan cyclic voltammetry--a proof-of-principle study.

Authors:  Christoph J Griessenauer; Su-Youne Chang; Susannah J Tye; Christopher J Kimble; Kevin E Bennet; Paul A Garris; Kendall H Lee
Journal:  J Neurosurg       Date:  2010-09       Impact factor: 5.115

Review 3.  Paraphilias and paraphilic disorders in Parkinson's disease: A systematic review of the literature.

Authors:  Paolo Solla; Marco Bortolato; Antonino Cannas; Cesare Salvatore Mulas; Francesco Marrosu
Journal:  Mov Disord       Date:  2015-03-11       Impact factor: 10.338

Review 4.  Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation.

Authors:  Susannah J Tye; Mark A Frye; Kendall H Lee
Journal:  Mayo Clin Proc       Date:  2009-06       Impact factor: 7.616

5.  Impulse control disorders following deep brain stimulation of the subthalamic nucleus in Parkinson's disease: clinical aspects.

Authors:  Polyvios Demetriades; Hugh Rickards; Andrea Eugenio Cavanna
Journal:  Parkinsons Dis       Date:  2011-02-20

6.  Imaging impulsivity in Parkinson's disease and the contribution of the subthalamic nucleus.

Authors:  Nicola Ray; Francesca Antonelli; Antonio P Strafella
Journal:  Parkinsons Dis       Date:  2011-06-05

7.  A Long Term Effects of a New Onset Psychosis after DBS Treated with Quetiapine in a Patient with Parkinson's Disease.

Authors:  Sara Piccoli; Giulia Perini; Silvia Pizzighello; Alec Vestri; Giovanni Ferri; Tommaso Toffanin; Halima Follador; Andrea Martinuzzi
Journal:  Psychiatry Investig       Date:  2015-01-12       Impact factor: 2.505

Review 8.  Challenges in PD Patient Management After DBS: A Pragmatic Review.

Authors:  Malco Rossi; Verónica Bruno; Julieta Arena; Ángel Cammarota; Marcelo Merello
Journal:  Mov Disord Clin Pract       Date:  2018-02-28

Review 9.  Hypersexuality in Parkinson's Disease: Systematic Review and Report of 7 New Cases.

Authors:  David Codling; Philip Shaw; Anthony S David
Journal:  Mov Disord Clin Pract       Date:  2015-04-30

10.  Timing of deep brain stimulation in Parkinson disease: a need for reappraisal?

Authors:  Ruth-Mary deSouza; Elena Moro; Anthony E Lang; Anthony H V Schapira
Journal:  Ann Neurol       Date:  2013-05       Impact factor: 10.422

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